26-Mar-2025
基于胆固醇代谢增强肿瘤免疫治疗的新靶点—PCSK9
ResearchPeer-Reviewed Publication
近日，首都医科大学附属北京友谊医院普外中心张忠涛教授/姚宏伟教授研究团队在Research发表了题为“Inhibition of PCSK9: A Promising Enhancer for Anti-PD-1/PD-L1 Immunotherapy”的综述论文。文章综述了前蛋白转化酶枯草溶菌素9（PCSK9）与胆固醇代谢的关系，系统讨论了抑制PCSK9增强抗程序性死亡受体-1及其配体（PD-1/PD-L1）免疫疗法的具体机制，并对这一治疗策略的研究方向进行了全面的总结和展望。
- Journal
- Research
- Funder
- National Natural Science Foundation of China, Training Fund for Open Projects at Clinical Institutes and Departments of Capital Medical University, Beijing Hospitals Authority Clinical Medicine Development of Special Funding Support, National Key Technologies R&D Program, Clinical Center for Colorectal Cancer, Capital Medical University, Xinjiang Uygur Autonomous Region “Tianchi Yingcai” Project