Cervical cancer, one of the most common malignancies in women worldwide, is primarily driven by human papillomavirus (HPV) infection. Researchers from China have identified a new subtype of keratinocytes, designated as PI3+S100A7+ cells, that appear early in HPV-positive cervical cancer and interact closely with immune cells to promote tumor progression. Using single-cell RNA sequencing, the team discovered how these cells alter the tumor environment and predict poor patient outcomes.

A recent collaborative study  led to the development of an innovative rain conceptual model using dual-frequency measurements from the WindRAD instrument aboard China’s FengYun-3E (FY-3E) satellite to quantify and correct rain-induced errors in wind measurements.

Abstract

Purpose – Investigation of the anomalies associated with crashes and jackpots in the Chinese stock market.

Design/methodology/approach – We propose a logit model to predict the events of crashes and jackpots in the Chinese stock market. The model introduces a new variable of the price-to-sales ratio and takes into account the market states, Up and Down.

Findings – The anomalies associated with crashes and jackpots are not related to variations in economic conditions, but are associated with limits to arbitrage. High-liquidity stocks have strong mispricing effects. The institutions’ speculative trading will push liquid stock prices further away from their fundamentals but avoid buying illiquid stocks with a higher probability of price crashes and jackpots.

Originality/value – We propose a logit model to predict the extreme events of both crash and jackpot in the Chinese stock market. Our model effectively disentangles from CRASHP and JACKP. Compared with the traditional model, it substantially enhances in-sample and out-sample predictions. Based on the predictions of the extreme events, we find two strong and robust pricing effects associated with ex ante CRASH and JACKP in the Chinese stock market.

As intrinsically carbon-free molecules, ammonia and hydrogen are considered as fuels for internal combustion engines, mainly for long-distance or off-road applications. These alternative fuels have different combustion characteristics, reactivity, and exhaust gas compositions compared to conventional fuels, raising questions about the suitability of lubricants in engines operating with them. The impact of ammonia, hydrogen, and their blends on lubricants in internal combustion engines is a relatively new topic, with few reference studies available. However, degradation processes of lubricants have been studied in the context of hydrocarbon fuels, and in compressors using ammonia as a refrigerant, for example. This work presents a review of the literature on engine oil degradation phenomena in relation to ammonia and hydrogen combustion characteristics. In particular, it highlights the current state of knowledge regarding compatibility with unburnt gases, elevated nitrogen oxide levels, and water. Additionally, it summarizes the latest insights into the contribution of lubricants to pollutant emissions.

By combining the merits of radiative cooling (RC) and evaporation cooling (EC), radiative coupled evaporative cooling (REC) has attracted considerable attention for sub-ambient cooling purposes. However, for outdoor devices, the interior heating power would increase the working temperature and fire risk, which would suppress their above-ambient heat dissipation capabilities and passive water cycle properties. In this work, we introduced a REC design based on an all-in-one photonic hydrogel for above-ambient heat dissipation and flame retardancy. Unlike conventional design RC film for heat dissipation with limited cooling power and fire risk, REC hydrogel can greatly improve the heat dissipation performance in the daytime with a high workload, indicating a 12.0 °C lower temperature than the RC film under the same conditions in the outdoor experiment. In the nighttime with a low workload, RC-assisted adsorption can improve atmospheric water harvesting to ensure EC in the daytime. In addition, our REC hydrogel significantly enhanced flame retardancy by absorbing heat without a corresponding temperature rise, thus mitigating fire risks. Thus, our design shows a promising solution for the thermal management of outdoor devices, delivering outstanding performance in both heat dissipation and flame retardancy.

Lead-acid batteries are indispensable in various applications, and it is crucial to monitor their status. However, the existing sensing units for lead-acid batteries are limited by their bulky size, slow response time, and lack of temperature sensing and compensation capabilities. In the current work, a compact GaN-based sensing device was proposed to simultaneously measure the electrolyte density and temperature. The device comprises a light-emitting diode (LED) and a photodetector (PD) integrated on a GaN-on-sapphire chip in a monolithic configuration. The forward voltage of the LED reflects the electrolyte temperature, while the photocurrent of the PD varies with electrolyte density due to optical reflection changes at the exposed sapphire interface. The measured signals were processed using a decoupling matrix to achieve temperature compensation. The device exhibits a sensitivity of −29.1 μA/(g/cm³) for density in the range of 1.09 g/cm³ to 1.29 g/cm³, and -1.07 mV/°C for temperature in the range of 25 to 45 °C. The performance of the device was also validated through comparisons with commercial meters and real-time monitoring during the charging and discharging of the batteries. The device has notable advantages in size, cost, and fast response/recovery time (134.3/201.4 ms), rendering it a promising tool for monitoring lead-acid batteries.

International students contribute to the academic and economic vitality of US higher education while facing exacerbated mental health challenges. Little is known about national trends in anxiety, depression, suicidal ideation and mental health service utilisation in this population. This study examined national trends in the prevalence of clinically significant anxiety, depression, suicidal ideation and service utilisation among international students in US higher education from 2015 to 2024.

A new study has identified a key enzyme that modulates tea plant immunity by regulating salicylic acid (SA), a critical plant defense hormone. The enzyme, CsUGT74B5, catalyzes the conversion of SA into a glucosylated form, salicylic acid 2-O-β-D-glucoside (SAG). This process reduces free SA levels, diminishing the plant’s resistance to anthracnose—a devastating fungal disease affecting tea crops worldwide. Experimental evidence showed that overexpressing CsUGT74B5 in tea leaves and model plants increased disease susceptibility, while applying SA externally enhanced pathogen defense. The findings reveal a previously unknown glucosylation mechanism that fine-tunes immune balance in tea plants.

Cold stress severely limits grapevine survival and fruit production. In this study, scientists discovered that the transcription factor VaWRKY65 plays a pivotal role in helping Vitis amurensis withstand freezing temperatures. The gene enhances cold tolerance through a dual mechanism: promoting the breakdown of starch into soluble sugars and stimulating the detoxification of reactive oxygen species (ROS). These combined effects improve cellular stability and energy balance under stress. The research also identified VaBAM3 and VaPOD36 as key downstream genes activated by VaWRKY65. This work uncovers how sugar metabolism and ROS scavenging are transcriptionally coordinated to strengthen cold resilience in grapevine.