Efficient luminescent stable chichibabin diradicaloid for near-infrared imaging and photothermal therapy
Peer-Reviewed Publication
Updates every hour. Last Updated: 4-Sep-2025 08:11 ET (4-Sep-2025 12:11 GMT/UTC)
Chichibabin diradicaloids, characterized by narrow band gaps and near-infrared (NIR) absorption, are limited in their practical applications in the biomedical field due to their instability and non-emissive properties. Herein, a symmetry-breaking and donor-modulating strategy yielded the highly stable Chichibabin diradicaloid TT-CzPh, with NIR luminescence (λem = 821 nm), 6.4% PLQY, and 87.5% PCE. Assembled into TT-CzPh NPs (82% PCE), it achieved NIR-guided tumor ablation in 4T1 mice, advancing their bioimaging and cancer phototherapy applications.
Scientists in South Korea experimentally demonstrated a single-gate electro-optic metasurface achieving efficient, wide-angle beam switching in the mid-infrared. The device modulates the Fermi level of monolayer graphene to control optical efficiencies across diffraction orders. Inverse design using a genetic algorithm and nonlocal quasinormal mode analysis enabled both high relative and absolute efficiencies with a wide 57° deflection angle. This work simplifies device architecture while retaining high performance, paving the way for practical, tunable optical beam routing applications.
Neonates who undergo enterostomy are at risk of complications that can lead to poor growth, fluid-electrolyte imbalance, and growth abnormalities if the postoperative nutrition is not optimally managed. To address this, researchers have developed a clinical guideline for postoperative nutrition support in neonates with enterostomy (2024). This standardized evidence-based guideline for infants with enterostomy presents 22 recommendations for postoperative nutritional management in this high-risk population.
A comprehensive review published in iMeta synthesizes current evidence on how the microbiome (including bacteria, viruses, and fungi) shapes cancer biology. The study highlights microbial influences on tumor development, immune modulation, therapy response, and potential diagnostic and therapeutic applications, underscoring the microbiome’s promise as a target for next-generation oncology strategies.
Jie Chen et al. from Sun Yat-Sen Memorial Hospital, of Sun Yat-sen University published a paper entitled "Psychological effects of virtual reality intervention on breast cancer patients with different personalities: A randomized controlled trial" in the International Journal of Nursing Sciences. A randomized controlled trial was conducted to systematically investigate the efficiency and safety of VR intervention with natural landscape content in alleviating negative emotions, aiming to provide new ideas and empirical evidence for psychological care of breast cancer patients.
Atopic dermatitis, a common chronic inflammatory skin disease, has an unclear etiology and may involve multiple factors such as genetic predisposition, immune abnormalities, and impaired skin barrier function. Currently, there is no specific medication available for the complete cure of atopic dermatitis. The current treatment approaches mainly focus on symptom relief and control rather than curative treatment. Some commonly used medications for atopic dermatitis, such as topical corticosteroids and immunosuppressants, may have certain adverse reactions and side effects. This review summarizes the research progress on natural extracts in the treatment of atopic dermatitis, aiming to provide a foundation for the development of safe and side-effect-free medications.
A research team from Songshan Lake Materials Laboratory introduced a new, eco-friendly method to transform carbon dioxide (CO₂, a major greenhouse gas) into useful high-performance plastics using a simple copper-based catalyst. Conducted under mild conditions at room temperature and ambient pressure, this process efficiently incorporates CO₂ into polymer materials that can be used in packaging, sensors, biomedical devices and more. The developed polymers are highly soluble, customizable, and can be quickly modified to create multifunctional materials. This innovative approach not only offers a sustainable way to recycle CO₂ but also opens new possibilities for producing advanced materials that support environmentally friendly manufacturing and help combat climate change.