Charité study analyzes 400 million years of enzyme evolution
Peer-Reviewed Publication
Updates every hour. Last Updated: 13-Nov-2025 11:11 ET (13-Nov-2025 16:11 GMT/UTC)
Enzymes catalyze chemical reactions in organisms - without which life would not be possible. Leveraging AlphaFold2 artificial intelligence, researchers at Charité – Universitätsmedizin Berlin have now succeeded in analyzing the laws of their evolution on a large scale. In the journal Nature*, they describe the parts of enzymes that change comparatively quickly and the parts that remain practically unchanged over time. These findings are relevant to the development of new antibiotics, for example.
Researchers at Southern University of Science and Technology developed an adaptive beam shaping method for laser micro-grooving to shape tiny grooves with sub-micron accuracy—even in hard-to-machine materials like silicon carbide.
By combining smart simulations and real-time adjustments, their system “teaches” lasers to self-compensation deviation between experimental and target results caused by diffraction and polarization, achieving 5× higher precision than traditional patterned laser ablation methods.
“Here, you can think of the laser as a shaped knife, and you can achieve the desired groove shape with a single stroke”, says Prof. Shaolin Xu.
To realize a sustainable low-carbon society, it is essential to establish a catalytic process that converts various concentrations of CO2 in combustion exhaust gases from thermal power plants and other sources into useful chemicals using renewable hydrogen. However, due to the high oxygen (O2) content (about 10%) in such exhaust gases, conventional catalytic methods face a major challenge in that H2 reacts preferentially with O2, making efficient CO2 conversion technically impossible. A research team led by Hokkaido University has developed a tandem system that continuously captures and converts CO2 in a wide concentration range, from atmospheric levels to exhaust gases. Their work is published in the journal Industrial Chemistry & Materials on June 13, 2025.