Comprehensive review illuminates promising future for Gemini surfactants in gene therapy delivery
Peer-Reviewed Publication
Updates every hour. Last Updated: 14-Nov-2025 15:11 ET (14-Nov-2025 20:11 GMT/UTC)
Gene delivery is a key area in biomedicine, where nucleic acids are delivered into cells to treat diseases by modulating genes. The low micelle concentration, effective nucleic acid complexation, and low immunogenicity make Gemini surfactants promising gene delivery vectors. Recently, a paper published in MedComm-Future Medicine summarizes strategies to improve the transfection efficiency or biocompatibility of Gemini surfactant vectors and explores their delivery mechanisms, thereby offering new insights into the field's development.
Research on the optical coherence manipulation has made significant progress, but the modulation rate of conventional tailoring technology is too low, which has become a key factor hindering its transition from laboratory to practical application. Here, we utilize lithium niobate films (LNF) modulator to achieve high-speed optical coherence manipulation based on its high-speed electro-optical modulation capability. Our experimental modulation rate reaches 350 kHz, which is about 20 times higher than the fastest modulation rate reported so far. This design strategy provides a simple rule for high-speed optical coherence manipulation based on electro-optical modulation, paving the way for further practical applications of optical coherence manipulation technology.
Achieving high efficiency, long operational lifetime, and excellent color purity is essential for organic light-emitting diode (OLED) materials used in next-generation display and lighting technologies, but these performance goals are increasingly difficult to reach with conventional trial-and-error design methods. In a new review published in Science Bulletin, researchers from Beijing Jiaotong University and Sichuan University present "Integrating AI into OLED Material Design: A Comprehensive Review of Computational Frameworks, Challenges, and Opportunities." The paper discusses how artificial intelligence (AI) can help overcome the limitations of traditional approaches, accelerate OLED material discovery, and offers a practical multi-level framework to guide future research in this field.
Focusing on the research progress of electro-synthetic value-added chemicals, this comment proposes lab strategies to enhance energy conversion efficiency, including catalyst screening, process monitoring, interface optimization, and mass transfer design, with analysis of implementation challenges. It also emphasizes that for industrial application of electrosynthesis technology, breakthroughs are needed in performance, lifespan, and cost, and multidimensional challenges such as modular integration, thermal and mass management, smart control, power configuration, and material separation must be addressed.
Extreme environments demand smarter sensors! A team from Zhejiang University has developed a laser-induced, in-situ fabrication method for thin-film temperature sensors with no complex layering, no extra coatings.
💡 Their approach forms conductive & antioxidative layers simultaneously, enabling real-time monitoring from −50 °C to 950 °C with remarkable stability.
📈 Just 1.2% drift over 20 hours under heat, shock, wear, and vibration.
A research team from the Korea Institute of Science and Technology (KIST, President Oh Sang-Rok), led by Dr. Hae Jung Son from the Advanced Photovoltaics Research Center, announced that they have developed a new dielectric additive-based coating technology that enables high-performance organic photovoltaics (OPVs) to be manufactured reliably regardless of seasonal humidity changes.