A study published in Cell advances understanding of how drugs shape vital cellular structures known as biomolecular condensates, blob-like mechanisms that drive gene regulation processes and have been linked to Alzheimer's, ALS and cancer.

A Virginia Tech-led team of international scientists has solved one of the last major mysteries in millipede evolution, revealing new clues about a group of animals that helped pave the way for life on land. The findings, published in Current Biology, complete the first evolutionary history of all living millipede orders. By combining genomic data from living species with morphological evidence from fossils, researchers traced the group's origins to nearly 460 million years ago — suggesting millipedes may have been present long before the oldest known millipede fossils.

Thermal diffusion—a fundamental physical process pervasive in applications ranging from electronics to industrial systems—is inherently irreversible under the second law of thermodynamics. As temperature gradients spontaneously smooth out over time, crucial information regarding the initial thermal state is permanently lost due to entropy increase. This fundamental information loss leads to a severe ill-posedness in inverse thermal problems, where infinitesimal errors in the final observation can cause enormous uncertainties in the reconstructed initial state.