ChatGPT 4o therapeutic chatbot ‘Amanda’ as effective as journaling for relationship support
Peer-Reviewed Publication
Updates every hour. Last Updated: 23-Nov-2025 10:11 ET (23-Nov-2025 15:11 GMT/UTC)
One of the first randomized controlled trials assessing the effectiveness of a large language model (LLM) chatbot ‘Amanda’ for relationship support shows that a single session of chatbot therapy can be as beneficial as a evidence-based journaling in assisting with relationship conflict resolution, according to a study published September 24, 2025 in the open-access journal PLOS Mental Health by Dr Laura Vowels from the University of Lausanne, Switzerland, and the University of Roehampton, United Kingdom, and colleagues.
Without Antibodies and Without Amplification: Ultra-fast Identification of Whole Proteins Using a Technology Developed at the Technion
Researchers at the Technion – Israel Institute of Technology have developed a groundbreaking technology for the ultra-fast identification of whole proteins, enabling rapid and precise protein diagnostics without the need for antibodies or molecular amplification. The innovation, led by Prof. Amit Meller and Dr. Neeraj Soni from the Faculty of Biomedical Engineering, represents a major step toward real-time proteome analysis and next-generation medical diagnostics.
Published in Nature Nanotechnology, the study introduces a nanopore-based platform that identifies proteins by reading their unique electrical “fingerprints” as they move through synthetic nanometer-scale pores. The system employs a “stick–slip” mechanism to control protein motion and uses machine learning algorithms to decode the resulting electrical signals, achieving identification speeds several orders of magnitude faster than existing methods.
The researchers demonstrated the approach using the amino acid cysteine, which is found in approximately 97% of human proteins—making the method broadly applicable across the human proteome. The technology, developed in collaboration with the University of Illinois and Rice University, holds promise for diverse clinical applications, including early cancer detection and personalized medicine through rapid blood-based protein analysis.
Supported by a European Research Council (ERC) Advanced Grant under the Horizon 2020 program, this breakthrough provides a new foundation for developing point-of-care systems capable of near-instant protein diagnostics—advancing both biomedical research and patient care.
The University of Texas at Austin has launched a new research consortium to help inform industry partners on options for more sustainable growth of this new industry. The consortium – called Collaborative Optimization & Management of Power Allocation, Surface & Subsurface strategies (COMPASS) – was announced last week at a data center workshop for industry leaders and policy makers led by the UT Bureau of Economic Geology, which is part of the Jackson School of Geosciences.
Social media has created a new pathway for achieving CEO celebrity that is very different from the traditional media-driven route. The research indicates that, unlike mainstream media, where journalists decide which CEOs make headlines, social media audiences reward CEOs who show up consistently, positively, and in diverse ways. With nearly five billion people using social media, the stakes for CEOs have never been higher.
Caltech physicists have created the largest qubit array ever assembled: 6,100 neutral-atom qubits trapped in a grid by lasers. Previous arrays of this kind contained only hundreds of qubits.
CAR T cells have revolutionized the treatment of certain blood cancers, but they often fail. A new study published in Nature (DOI: 10.1038/s41586-025-09507-9) by scientists at CeMM and the Medical University of Vienna introduces a novel CRISPR screening platform, which discovered unexpected genetic edits that make CAR T cells more effective as cancer therapies