Neuroblastoma kills more children under one year of age than any other extracranial solid tumor, and high-risk cases have resisted meaningful improvement in survival for decades. A team at the Hebrew University of Jerusalem has now identified a molecular accomplice: neuronal nitric oxide synthase, or nNOS, which feeds the mTOR growth-signaling pathway through nitrosative stress. Blocking nNOS, either pharmacologically with the compound BA-101 or genetically with siRNA, silenced mTOR signaling and crippled malignant behavior in human neuroblastoma cells. In a xenograft mouse model, BA-101 shrank tumors dramatically (p < 0.001). The nNOS–mTOR axis emerges as a new and targetable vulnerability. NeuroNOS Ltd., which partly funded this work, has obtained a license for the patent applications of the BA-101 molecule filed by Yissum (The Hebrew University Technology Transfer Company). The authors, in collaboration with NeuroNOS, have also demonstrated the therapeutic efficacy of BA-101 in glioblastoma.

Key takeaways:

- New survey results from The Ohio State University Wexner Medical Center find public openness to AI in health care has decreased, with only 42% of adults supportive in 2026 compared to 52% in 2024.

- Despite concerns about AI's accuracy and understanding of individual health history, 51% of adults surveyed relied on AI for important health decisions without consulting a medical professional.

- Survey participants commonly use AI to understand symptoms (62%), explain test results (44%), compare treatment options (25%), and prepare for medical appointments (20%).

Artificial intelligence is playing an ever larger role in the delivery of psychotherapy. An interdisciplinary team of University of Utah researchers has built a framework for assessing varying levels of automation in a mental health field reliant on human interaction.

Antibiotic pollution is emerging as a serious global threat, contaminating water systems and contributing to the rise of drug-resistant bacteria. Now, researchers have developed a powerful artificial intelligence tool that can predict how effectively biochar materials break down antibiotics, offering a faster and smarter way to design environmental cleanup technologies.

Biochar, a carbon-rich material made from agricultural waste, has long been valued for improving soil and capturing carbon. Now, a new review highlights a less visible but potentially transformative property that could redefine its role in environmental technology: its ability to move electrons.

A new study reveals that biochar can actively regulate the movement of antibiotics in soil, offering a promising strategy to reduce agricultural pollution and protect water resources.

Urban green spaces such as parks, gardens, and residential lawns play an essential role in supporting biodiversity, storing carbon, and improving human well-being. However, rapid urbanization is degrading these soils, reducing their fertility and disrupting natural nutrient cycles. A new study reveals that combining biochar and compost can restore soil health, but only under the right conditions, and fungi play a decisive role in determining success.

A new study demonstrates that agricultural waste can be transformed into a powerful, eco-friendly catalyst that dramatically improves the removal of stubborn chemical pollutants from water. Researchers developed a nitrogen-doped biochar made from cotton hulls that enhances ozone-based water treatment efficiency by more than 100 times, offering a promising solution for tackling emerging contaminants.

A five-year field study reveals that biochar can do far more than improve soil chemistry. It can reorganize entire soil ecosystems, creating lasting benefits for agriculture and environmental sustainability.