Researchers have developed fluorescent molecules that permit imaging how DNA is packaged inside living cells at unprecedented resolution, and in preserved cells, close to the width of the double helix itself. The advance raises the possibility that one day they could train an AI to look at how DNA occupies three-dimensional space inside cells for diagnosing and treating cancer and other types of conditions.

Scientists from Gladstone Institutes, UC San Francisco, and Stanford University, in collaboration with Biohub, have unveiled a massive, high-resolution functional map of human immune cells that promises to transform our understanding of how genetics control health and disease. Published in the journal Cell, the study represents a landmark achievement in immunology and genomics. By systematically stress-testing genes across the genome in 22 million human immune cells, scientists moved beyond mere DNA sequencing to decode the dynamic circuits that govern how these genes actually work in the context of health and disease.

Electrochemical CO₂ reduction to formate is a promising route to convert greenhouse gases into value-added liquid chemicals, but persistent cell voltage rise during operation has long limited high-concentration product accumulation and long-term stability. A research team led by scientists from the University of Science and Technology Beijing has identified that unidirectional cation migration across the ion exchange membrane is the dominant cause of voltage growth, and proposed a simple yet effective "concentration-gradient" strategy. By pairing high-concentration anolyte (3.37 mol·L⁻¹) with low-concentration catholyte (0.5 mol·L⁻¹) to generate reverse diffusion potential, the strategy confines cell voltage fluctuations within ±0.5 V and enables over 30 hours of continuous stable operation — 3 to 4 times longer than conventional systems. Normalized formate productivity reaches 200% of the average level, and the strategy works universally across cation-based electrolyte systems.

Phosphine (PH₃) is a deadly industrial byproduct that poses a severe threat to human health and the environment. A research team from Yunnan Minzu University and Kunming University of Science and Technology has developed a sustainable "waste-to-wealth" strategy that captures toxic PH₃ tail gas and transforms it in situ into a robust Ni₂P/Ni₅P₄ heterostructure electrocatalyst. This innovative approach not only achieves high-efficiency gas purification but also provides a low-cost, high-performance solution for green hydrogen production, bridging the gap between pollution control and clean energy.

Nano-antennas make living cells light up brighter and faster

Researchers at Delft University of Technology have demonstrated for the first time that nano-antennas can enhance the fluorescence of proteins in living human and other mammalian cells. Scientists already use smart fluorescent proteins that light up when the electrical voltage across a nerve cell changes. By placing nano-antennas close to these light-emitting proteins, researchers can monitor processes inside cells with much greater precision. The discovery adds a new tool for revealing electrical signals in the brain: through nanotechnology as well as genetic engineering. The research has been published in Advanced Materials.

What do wind turbines, EV batteries, military equipment and your smartphone have in common? Probably more than you think. To be manufactured, these products require critical minerals that are found beneath our feet. But gaining access to these minerals, which are crucial and in high demand worldwide, is not a simple process. Currently, the United States relies heavily on importing these materials, which can be delayed for various reasons. As a result, finding domestic sources of critical minerals is a priority. But finding new sources of critical minerals can take years of drilling, sample collection and laboratory testing before geologists know whether a site contains sufficient deposits to merit development. Researchers at Texas A&M University are working to change that.