This study introduces TEAM (Targeted Elimination and Microcell-Mediated Transfer), a novel programmable platform that enables precise chromosome replacement in mammalian cells. By combining CRISPR/Cas9-mediated chromosome elimination with microcell-mediated chromosome transfer (MMCT), researchers successfully demonstrated intra-species chromosome stability while uncovering fundamental barriers to cross-species chromosome engineering.

Short-chain perfluorinated and polyfluorinated alkyl compounds (PFAS) such as perfluorobutanoic acid (PFBA) are increasingly entering the environment via various pathways and contaminating groundwater and drinking water. Because PFAS are highly mobile, removing them has so far required a great deal of effort. But a research team at the Helmholtz Centre for Environmental Research (UFZ) has developed a new technology to do so. According to an article recently published in Chemical Engineering Journal, the new process is more environmentally friendly and less energy-intensive.

Rising energy transmission needs are evolving pipelines into integrated, coupled Energy Transportation Systems (ETS), where leakage risks demand real-time monitoring. Data-driven methods excel in leakage diagnosis but lack a systematic review from pipelines to ETS. This paper reviews relevant advances, analyzes detection and localization methods, and suggests future research directions.

The development of highly stable zinc (Zn) anodes under high discharge depth (DOD) is crucial for the practical application of aqueous zinc metal batteries (AZMBs). However, the disordered plating/stripping behavior of Zn metal anodes caused by localized electron accumulation or depletion at the interface significantly hinders their practicality under high areal capacity conditions. This work reports a work-function-guided chemical interface for Zn anodes with high area capacity. Induced by interfacial work-function difference, the ohmic contact constructs electron bridge during band alignment. This electron transport provides abundant reaction sites for uniform Zn²⁺ plating/stripping at the interface, suppressing cracking of interface. As a result, the designed interface ensures stable cycling at a capacity of 30 mAh cm^–2 (52% DOD) and 50 mAh cm^–2 (85% DOD) without obvious interfacial morphology deterioration. As a practical validation, a 370 mAh Zn||iodine (Zn||I₂) pouch cell operates effectively at a remarkable areal capacity of 4.625 mAh cm^–2, highlighting the advancement of interface design in specific electron transport mode for practical anode performance.

A new paper in Nature Chemistry describes a molecular material that combines a stable internal magnetic structure with almost no external magnetic field. This could prove relevant for energy‑efficient electronics and spintronics.