Lipid‐based nanoplatforms: Revolutionary tools for hepatology from design to clinical challenges
Peer-Reviewed Publication
Updates every hour. Last Updated: 25-Nov-2025 21:11 ET (26-Nov-2025 02:11 GMT/UTC)
In a review article published in MedComm – Biomaterials and Applications, a team of researchers from multiple institutions in China comprehensively explores lipid‐based nanocarriers (LBNCs) as a transformative solution for liver diseases. The review details the rational design of various LBNC types (including liposomes, micelles, nanoemulsions, and more), their preclinical and clinical applications in treating conditions like hepatitis, liver fibrosis, and hepatocellular carcinoma (HCC), as well as the key challenges hindering their translation from laboratory to clinic. It also proposes forward‐looking strategies, such as AI‐driven lipid optimization, to accelerate the clinical adoption of LBNC‐based therapies.
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