Tech & Engineering
Updates every hour. Last Updated: 27-Jan-2026 07:11 ET (27-Jan-2026 12:11 GMT/UTC)
A new strategy for immune tolerance
Nano Life Science Institute (NanoLSI), Kanazawa UniversityPeer-Reviewed Publication
A research team at the Nano Life Science Institute (WPI-NanoLSI) and the Faculty of Medicine at Kanazawa University has developed a new class of engineered extracellular vesicles (EVs) capable of inducing antigen-specific regulatory T cells (Tregs), the immune cells that play a central role in suppressing excessive immune responses. The findings, now published in Drug Delivery, may pave the way for next-generation therapies for autoimmune and allergic diseases, where unwanted immune activation must be precisely controlled.
- Journal
- Drug Delivery
New microfluidics technology enables highly uniform DNA condensate formation
Chuo UniversityPeer-Reviewed Publication
Abstract:
A research group led by Professor Hiroaki SUZUKI and Takeshi HAYAKAWA from the Faculty of Science and Engineering at Chuo University, graduate student Zhitai HUANG, graduate students Kanji KANEKO (at the time) and Ryotaro YONEYAMA (at the time), together with Specially Appointed Assistant Professor Tomoya MARUYAMA from the Research Center for Autonomous Systems Materialogy (ASMat), Institute of Integrated Research (IIR), Institute of Science Tokyo, and Professor Masahiro TAKINOUE from the Laboratory for Chemistry and Life Science, Institute of Integrated Research, Institute of Science Tokyo, has developed a novel and highly accessible technology for producing uniform Biomolecular Condensates*1) using a simple, low-cost vibration platform.
- Journal
- Materials Horizons
- Funder
- Japan Society for the Promotion of Science, Japan Keirin Autorace (JKA) promotion fund, The Institute of Science and Engineering of Chuo University
Investigation on three-dimensional unsteady flow characteristics during TBCC inlet mode transition using fast-responding PSP
Tsinghua University PressThe mode transition of combined-cycle inlets, governed by sidewall constraints, is inherently characterized by significant three-dimensional (3D) unsteady flow phenomena that elude capture by conventional two-dimensional (2D) diagnostics or single-point transducers. This research published in the Chinese Journal of Aeronautics utilizes fast-response pressure-sensitive paint (PSP) to conduct dynamic measurements on the wall pressure field of a typical over-under TBCC inlet during mode transition, successfully elucidating the 3D characteristics of these unsteady flows.
- Journal
- Chinese Journal of Aeronautics
AI enabled launch vehicles: Next potential disruptive technology after reusability
Tsinghua University PressPeer-Reviewed Publication
In the era of global space industry's rapid expansion, reusable launch technology addresses cost reduction, but achieving high launch cadence and flight reliability remains critical. This study published in the Chinese Journal of Aeronautics (Volume 38, Issue 10, October 2025, https://doi.org/10.1016/j.cja.2025.103756), proposes that artificial intelligence (AI) would be the potential disruptive technology to solve these challenges. AI enables transformative capabilities for launch vehicles are pointed out in four domains: Agile launch operations enabling automate testing, fault diagnosis, and decision-making for targeting hour-level launch cycles and minute-level fault resolution; High-reliability flight enabling real-time autonomous fault diagnosis, mission replanning, and fault-tolerant control within seconds during anomalies, potentially improving reliability by 1-2 orders of magnitude; Rapid maintenance enabling real-time health monitoring and lifespan prediction for swift re-launch decisions; and Efficient space traffic management enabling predict/resolve orbital conflicts amid growing congestion from satellites and debris. The key challenges for AI applications are analyzed as well, including multi-system coupling, uncertain failure modes and narrow flight corridors, limited sensor data, and massive heterogeneous data processing. Finally, the study also proposes that AI promises substantial efficiency gains in launch vehicle design, manufacturing, and testing through multidisciplinary optimization and reduced reliance on physical testing.
- Journal
- Chinese Journal of Aeronautics
Single-hole study decodes micro-blowing drag-reduction mechanism in supersonic turbulent flows
Tsinghua University PressPore-scale mechanisms of drag reduction by micro-blowing have rarely been explored. A direct numerical simulation (DNS) study, published in the Chinese Journal of Aeronautics, is performed to uncover the fundamental physics of single-hole micro-blowing in a supersonic turbulent boundary layer. Results reveal a dual-regime drag-reduction mechanism: upstream reduction driven by adverse pressure gradients and downstream reduction dominated by the formation of a low-speed air film. A detailed vortex-interaction analysis further explains how micro-blowing sustains stable drag-reduction performance under turbulent vortex interference.
- Journal
- Chinese Journal of Aeronautics
Heterointerface engineering of n-heterocyclic carbene-derived n/metal dual-doped carbon materials for superior electromagnetic wave absorption
Tsinghua University PressN-heterocyclic carbene (NHC) polymers, characterized by abundant nitrogen sources, tunable metal centers and excellent chemical stability, serve as ideal precursors for metal-incorporated N-doped carbon materials. Therefore, NHC-derived N/metal dual-doped carbon materials (CN-X-700, X=Cu, Cu/Co and Co) are considered to be promising electromagnetic wave (EMW) absorbers. The Cu/Co bimetallic nanoparticles are anchored on two-dimensional carbon nanoribbon, thereby generating abundant heterointerfaces, which is conductive to EMW absorption. This study reveals the intrinsic relationship between heterointerfaces, multi-loss mechanisms and EMW dissipation, providing a novel structural regulation strategy for designing high-performance carbon-based microwave absorbers.
- Journal
- Nano Research