See through large animal tissues: overcoming biological barriers
Peer-Reviewed Publication
Updates every hour. Last Updated: 25-Nov-2025 16:11 ET (25-Nov-2025 21:11 GMT/UTC)
Focusing on the methodological challenges in adapting tissue optical clearing technology to large animals, this review systematically examines the key bottlenecks in transitioning from rodents to large animals, summarizes representative applications in neural circuit mapping and sensory organ visualization in large animal, and offers perspectives on future research directions.
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