A new study uses 3D tumor spheroid models to screen 365 human cytokines, finding TGFB1 inhibits pancreatic ductal adenocarcinoma (PDAC) growth specifically in 3D cultures. Researchers also identify PADI2 as a critical survival factor induced by TGFB1 in 3D, offering potential therapeutic targets for this lethal cancer.

Heavy metals, an indispensable part of many industries, are serious environmental and public health threats. Detecting these contaminants, which is essential for tackling them effectively, often requires sophisticated equipment and expensive testing procedures. To tackle this, researchers have used five commonly available medicinal plants in India and presented a simple and time-efficient approach to developing highly sensitive, eco-friendly carbon nanoparticles (CNPs), which contain nanosized carbon elements. Other than the optical and sensing features, these CNPs also exhibited biomedical capabilities. 

Dyes are used to colour papers, leather products, garments, and are also employed in the rubber and cosmetic industries. But what happens after these dyes have served their purpose? Billions of tons of dye-containing wastewater enter water systems every year, eventually rendering them unfit for human and animal use. They can also lead to serious health issues such as breathing problems, jaundice, and cancer. As an effort to tackle this issue, researchers have developed advanced materials, which act like microscopic sponges, as a promising solution to industrial wastewater treatment. 

A University of Florida-led study of 1,051 Floridians finds strategic environmental communication significantly boosts public support for roadside pollinator habitat, with agricultural benefit frames driving the strongest attitudinal shifts.