A research team from the Department of Pharmacology and Pharmacy, LKS Faculty of Medicine of the University of Hong Kong (HKUMed), has found that nitrogen-containing bisphosphonates (NBPs), a medication widely used in the treatment of osteoporosis, may significantly reduce the risk of Alzheimer’s disease and related dementias (ADRD) in older adults with osteoporosis or fragility fractures. This drug repurposing approach offers a promising avenue for the prevention of ADRD, potentially alleviating the global burden of these conditions. The research findings were published in Alzheimer’s & Dementia.

Acupoints have long been viewed as fixed locations for therapeutic stimulation, yet emerging evidence suggests they are dynamic biological sites that change with disease states.

Findings show TB-related lung lesions can create protected niches for bacteria, helping explain why some patients develop new infections even after treatment. Prevention, early diagnosis, completing treatment as prescribed and appropriate follow-up care remain important in reducing long-term health risks.

This study investigates the causal relationship between epilepsy subtypes and brain connectivity within resting-state networks using a bidirectional Mendelian randomization framework. By leveraging large-scale genetic and neuroimaging datasets, the researchers provide a more reliable assessment of causality beyond traditional observational studies.

The results demonstrate that genetic generalized epilepsy is associated with functional alterations in attention and motor-related brain networks, while brain connectivity changes do not appear to causally drive epilepsy. These findings deepen our understanding of epilepsy as a network-level disorder and suggest new avenues for targeted intervention and precision medicine.

A new review published in the journal Magnetic Medicine indicates that static magnetic fields (SMF) and alternating magnetic fields (AMF) are expected to provide a non-invasive new method for organ preservation, addressing many limitations of current organ preservation technologies and bringing new hope to the field of organ transplantation.