Tiny fish-inspired robots work as team to deliver medicine to multi-point 3D lesions
Peer-Reviewed Publication
Updates every hour. Last Updated: 24-Dec-2025 12:11 ET (24-Dec-2025 17:11 GMT/UTC)
Researchers have developed miniature magnetic robots that mimic fish behavior, working together as coordinated swarms to deliver drugs precisely and efficiently to tissue. The breakthrough could transform treatment of conditions where individual tiny robots lack sufficient coverage area for effective therapy.
Professor Xiaokong Liu's team at Jilin University proposed an "activation-quenching" strategy for dynamic covalent chemistry, achieving precise and controllable "on-off" switching of dynamic bond exchange reactions in dynamic covalent polymers (covalent adaptive networks or CANs). This strategy enables the polymer network to reversibly switch between a remodelable dynamic state and a highly stable thermosetting state on demand, effectively balancing the material's remodeling processability and thermal stability, and providing a novel approach to resolving the contradiction between sustainability and stability in dynamic covalent polymers. The article was published as an open access research article in CCS Chemistry, the flagship journal of the Chinese Chemical Society.