Could physics theory better inform defensive basketball positioning?
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Updates every hour. Last Updated: 20-Jun-2025 16:10 ET (20-Jun-2025 20:10 GMT/UTC)
Insilico Medicine, a clinical-stage biotechnology company driven by generative artificial intelligence (AI), today announces the development of novel pan-KRAS inhibitors of new chemotypes through structure-based drug design, scaffold hopping combined with intense molecular modeling, empowered by the generative chemistry methods of Chemistry42, Insilico’s proprietary generative chemistry platform. Developed in the joint efforts of artificial intelligence and human expertise, the candidate compounds demonstrated pan-KRAS inhibition with potency in the upper nanomolar range. The results have been recently published on ACS Medicinal Chemistry Letters.
A research team led by Peter Baum from the University of Konstanz aims to film and visualize previously hidden processes at the atomic level in space and time. The European Research Council awarded Baum an Advanced Grant of 3.1 million euros to develop innovative methods in ultrafast electron microscopy.
For the second time, Würzburg chemistry professor Frank Würthner has received a prestigious award from the European Research Council: the ERC Advanced Grant is endowed with 2.5 million euros. The professor is pursuing an ambitious goal: he wants to synthesise schwarzites, novel carbon-based nanomaterials with unique properties.
Wildfires pollute waterways and could affect their ability to sequester carbon, recent University of British Columbia research shows.
UBC researchers discuss how wildfires affect our waters, including increasing compounds like arsenic and lead as well as nutrients such as nitrogen and phosphorus in the Fraser River, and what this means in a changing climate.