Inside living cells, molecules are constantly on the move – binding, diffusing, interacting. An international competition, the 2^nd AnDi Challenge, has now delivered a systematic comparison of analytical methods for single-molecule motion analysis, highlighting both the current strengths and the pressing challenges in this rapidly advancing field.

The Korea Research Institute of Standards and Science (KRISS, President Lee Ho Seong) has successfully developed a length measurement system that achieves a level of precision approaching the theoretical limit allowed by quantum physics.

Efficient stoves not only reduce CO₂ emissions and conserve valuable resources, but their use also leads to better indoor air quality and potentially reduces health risks, especially for women. This is shown in a study conducted by the Leibniz Institute for Tropospheric Research (TROPOS), Buana e.V., and Safer Rwanda, which has now been published in the journal Scientific Reports from the Nature Portfolio. The study compares air quality and health effects of efficient stoves and traditional cooking methods in rural communities in Rwanda. It was supported by atmosfair, a German non-profit organization supporting offsetting of CO₂ with projects such as the production and distribution of improved cookstoves. The study was funded by Chiesi Onlus Foundation.

Temporary tattoos aren’t just for kids anymore — semi-permanent versions have become a favorite among adults who don’t want the commitment of the real thing. Now, researchers reporting in ACS Sensors have created their own temporary tattoo sticker that has a hidden, but possibly lifesaving, purpose: detecting the presence of one drug used to “spike” alcoholic beverages and facilitate sexual assault. The sticker responds within 1 second to even low concentrations of the drug γ-hydroxybutyrate (GHB).

The Helfrich theory of membrane bending, supported by molecular dynamics simulations, is a promising approach for evaluating mechanical properties of graphene nanosheets, report researchers from Institute of Science Tokyo. This hybrid approach allows direct evaluation of bending rigidities of graphene nanosheets, even with lattice defects, without requiring experimental tests, offering valuable insights for designing novel two-dimensional materials with tailored mechanical properties.

In a step toward smarter materials, researchers from Institute of Science Tokyo collaborated with researchers from Switzerland to develop a smart hinge-like molecule that can indicate mechanical stress in polymeric materials through fluorescence. Using a framework of [2.2]paracyclophane and two pyrene-based luminophores (light-emitting compounds), the developed molecule exhibits excellent stress-sensing with high durability—offering a powerful tool for real-time monitoring of mechanical damage.