GLP-1 receptor agonists or SGLT2 inhibitors and nonarteritic anterior ischemic optic neuropathy
Peer-Reviewed Publication
Updates every hour. Last Updated: 27-May-2026 07:15 ET (27-May-2026 11:15 GMT/UTC)
The enzyme RNA polymerase reads a DNA template to build RNA one nucleotide at a time, but how it performs its core chemistry is unresolved. New cryo-EM structures capture the enzyme in intermediate states, showing for the first time that RNA polymerase catalyzes reactions through the precise alignment of substrates and using a coordinated chain of water molecules that act as a proton shuttle. Because this mechanism is conserved across all life, the findings provide a universal blueprint for gene expression and explain how certain mutations disrupt transcription.
Researchers from the Department of Physical Chemistry at the Fritz Haber Institute and Freie Universität Berlin have revealed the arrangement of water molecules at the interface between liquid water and air. Their findings help to better understand interfacial chemistry, which is largely determined by the specific arrangement of the water molecules. The study shows that one parameter in particular - one that has been neglected until now - is of fundamental importance: the water twist.
30 April 2026 / Kiel / Mindelo. Tomorrow, fourteen Master’s students in the West African Master’s programme ‘Climate Change and Marine Sciences’ will begin their two-week training and research voyage aboard the research vessel POLARSTERN. Travelling from Mindelo in Cabo Verde to Bremerhaven, Germany, they will carry out physical, biogeochemical and biological measurements together with ten experienced scientists. This is the fourth time that the Floating University is taking place under the leadership of GEOMAR Helmholtz Centre for Ocean Research Kiel. This initiative significantly contributes to the goals of the UN Decade of Ocean Science and is funded by the German Federal Ministry of Research, Technology and Space (BMFTR) as part of the WASCAL programme (West African Science Service Centre on Climate Change and Adapted Land Use).
A physics-inspired model calibrated on 40 years of US congressional data pinpoints a spending threshold of roughly 1.8 million USD at which campaigns stop influencing who wins and start fueling polarization instead.