University of Rochester and RIT develop experimental quantum communications network
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The study shows that digitalization is not contributing to achieving the energy transition
Biophysicists figure out how bacteria form robust patterns despite changing environmental conditions and fluctuating protein concentrations.
Scientists have unveiled the magnesium-bound crystal structure of Akkermansia muciniphila sialidase Amuc_1547, a key enzyme enabling gut bacteria to degrade protective mucins. The study reveals a unique metal-binding pocket, a carbohydrate-binding domain, and an unconventional catalytic mechanism. These findings advance understanding of gut microbiota adaptation and offer potential pathways for therapies targeting metabolic diseases linked to mucin metabolism.