Tuberculosis: Scientists develop novel drug candidate for combating resistant pathogens
Peer-Reviewed Publication
Updates every hour. Last Updated: 2-May-2026 18:16 ET (2-May-2026 22:16 GMT/UTC)
Researchers at Martin Luther University Halle-Wittenberg (MLU) have developed a promising new substance for targeting bacteria that cause tuberculosis. The team have produced a compound that inhibits the pathogens’ ability to produce energy and causes them to die. Established drugs work in a similar fashion, but the pathogen is becoming increasingly resistant to these medications. The study was conducted jointly with other researchers from Germany, the USA and Canada and its findings were published in the “Journal of Medicinal Chemistry”.
Rising greenhouse gas emissions could see the size of extreme floods in the Central Himalayas increase by between as much as 73% and 84% by the end of this century.
Ultraprecise fluorescence nanoscopy techniques such as MINFLUX and RASTMIN are enabling molecular-scale imaging and tracking in biologically relevant conditions. However, their implementation is challenging and requires stabilizing the position of the sample during the relatively long measurement times of minutes or tens of minutes. Scientists have developed an open-source system based on commonly available hardware that achieves sub-nanometric stabilization of the sample position for hours, opening the way for widespread application of single-molecule localization with true nanometer precision.
With climate change and higher incidence of crop diseases, global cocoa production and supply is being threatened. A research team from the National University of Singapore (NUS), motivated by these reports, set out to enhance the taste of carob, making it a more appealing and sustainable alternative to cocoa.
The NUS team, led by Associate Professor Liu Shao Quan from the Department of Food Science and Technology at the NUS Faculty of Science, has developed two innovative techniques to enhance the taste of carob pulp.
“Our carob-based innovation meets the relatively untapped and nascent market of alternative chocolate sources. Additionally, our new techniques improve the taste of carob itself, without the use of additives such as flavourings. So, consumers can have the best of both worlds – better flavour and a simple ingredients list. With these innovations, we aim to make a meaningful contribution towards addressing the current challenges and needs of the chocolate industry,” said Assoc Prof Liu.
LMU physicists have developed a model to describe how reaction-diffusion networks develop “foams”.
For decades, nuclear physicists believed that “Islands of Inversion” — regions where the normal rules of nuclear structure suddenly break down — were found mostly in neutron-rich isotopes. In these unusual pockets of the nuclear chart, magic numbers disappear, spherical shapes collapse, and nuclei unexpectedly transform into strongly deformed objects. So far, all such islands found were exotic nuclei such as beryllium-12 (N = 8), magnesium-32 (N = 20), and chromium-64 (N = 40), all of which are far away from the stable nuclei found in nature.
But now, a study recently carried out by an international collaboration of the Center for Exotic Nuclear Studies, Institute for Basic Science (IBS), University of Padova, Michigan State University, University of Strasbourg and other institutions have uncovered something no one had seen before: an Island of Inversion hiding in one of the most symmetric regions of all, where the number of protons equals the number of neutrons.