Drug candidate eliminates breast cancer tumors in mice in a single dose
Peer-Reviewed Publication
Updates every hour. Last Updated: 13-May-2025 08:09 ET (13-May-2025 12:09 GMT/UTC)
Despite significant therapeutic advances, breast cancer remains a leading cause of cancer-related death in women. Treatment typically involves surgery and follow-up hormone therapy, but late effects of these treatments include osteoporosis, sexual dysfunction and blood clots. Now, researchers reporting in ACS Central Science have created a novel treatment that eliminated small breast tumors and significantly shrank large tumors in mice in a single dose, without problematic side effects.
Inductively coupled plasma mass spectrometry (ICP-MS) is prominently used for analyzing elemental composition in individual cells. However, the conventional sample introduction system of ICP-MS causes damage to large mammalian cells. Now, researchers from Japan suggest an efficient method of introducing mammalian cells using a microdroplet generator (µDG) that maintains the cell’s structure without compromising elemental composition. These findings can open new avenues for the diagnosis and prognosis of diseases.
Oral mucositis is a painful condition in which the mucous membranes inside the mouth become inflamed. To help alleviate this, researchers at the Tokyo University of Science (TUS) have developed a mucoadhesive film using xyloglucan and antioxidant-rich green tea extract containing catechins. With its strong adhesive properties, the film directly adheres to the affected area. Made from accessible ingredients, this solution could provide localized relief and improve the quality of life for patients.