Understanding how cancer cells use water pressure to move through the body
Peer-Reviewed Publication
Updates every hour. Last Updated: 5-May-2026 11:16 ET (5-May-2026 15:16 GMT/UTC)
Cancer cells often invade different tissues by forming rounded protrusions called blebs. However, the exact mechanism behind this expansion remained unclear. Now, researchers at Kyushu University have discovered that cancer cells use protein clusters to create water pressure inside blebs, which pushes the cell membrane outward, enabling rapid movement. This newly identified mechanism, named “CaMKII-based osmotically-driven deformation or CODE,” reveals a unique physical process that drives the spread of cancer cells inside the body.
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