NUS Medicine study: Inability of cells to recycle fats can spell disease
Peer-Reviewed Publication
Updates every hour. Last Updated: 4-May-2025 17:09 ET (4-May-2025 21:09 GMT/UTC)
Accumulation of fat molecules is detrimental to the cell. Researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), have made a breakthrough in understanding how our cells manage to stay healthy by recycling important fat molecules. Their study, published in the journal Proceedings of the National Academy of Sciences (PNAS), reveals how a protein called Spinster homolog 1 (Spns1) helps transport fats out of cell compartments known as lysosomes.
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