Tiny, fatty and vital – meet the medicine courier of the future
Peer-Reviewed Publication
Updates every hour. Last Updated: 21-Oct-2025 17:11 ET (21-Oct-2025 21:11 GMT/UTC)
Most people associate Hong Kong with skyscrapers and shopping malls, but a small population of feral water buffalo calls the marshlands of South Lantau Island home. And they’re sparking a mix of curiosity, concern, and connection among locals.
This study presents a novel method to produce genetically modified rats by generating functional rat sperm in germ cell-deficient mice via blastocyst complementation with rat ES cells. Fluorescent rat ES cell lines were established, validated for pluripotency, and used to generate rat sperm in chimeric mice. The sperm successfully fertilized rat oocytes, producing viable offspring. This technique bypasses traditional chimera generation and reduces cost, offering an efficient platform for complex rat genetic engineering using ES cells.
Australian scientists have successfully developed a research system that uses ‘biological artificial intelligence’ to design and evolve molecules with new or improved functions directly in mammal cells. The researchers said this system provides a powerful new tool that will help scientists develop more specific and effective research tools or gene therapies.
POSTECH and Linyi University develop ‘SLY,’ a Probe That Glows Yellow Only in Tumor Cells.