New single‑cell technique reveals how tuberculosis‑like bacteria alter human cells
Peer-Reviewed Publication
Updates every hour. Last Updated: 19-Jun-2026 11:15 ET (19-Jun-2026 15:15 GMT/UTC)
Researchers at the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine) have developed a revolutionary new method to improve compact gene-editing tools known as base editors, which enable smaller, more precise DNA correction tools that may be safer for future gene therapies.Researchers at the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine) have developed a revolutionary new method to improve compact gene-editing tools known as base editors, which enable smaller, more precise DNA correction tools that may be safer for future gene therapies.
The rocks beneath our feet are leaving a hidden signature in the shells of marine snails along Australia’s ancient coastline, according to new research led by Adelaide University scientists.
Every year, millions of people are diagnosed with cancer globally; however, current treatments are limited by disease complexity. A study published March 17th in the open-access journal in PLOS Biology by Tianyu Jiang at Shandong University, Qingdao, China and colleagues suggests that Escherichia coli Nissle 1917 (EcN) may be engineered with anticancer agents to treat cancerous tumors in mice.
Scientists at HSE University have identified a molecular mechanism underlying aggressive breast cancer. They found that the signals supporting tumour growth originate not from the tumour itself but from its microenvironment. The researchers also demonstrated that reduced levels of the IGFBP6 protein in the tumour microenvironment lead to the accumulation of macrophages—immune cells associated with a higher risk of cancer recurrence. These findings already make it possible to assess patient risk more accurately and may, in the future, enable the development of drugs that target cells of the tumour microenvironment. The study has been published in Current Drug Therapy.
In a single experiment, scientists can decipher the entire genomes of many patient samples, animal models or cultured cells. To fully realize the potential to study biology at this unprecedented scale, researchers must be equipped to analyze the titanic troves of data generated by these new methods.
Scientists at Sanford Burnham Prebys Medical Discovery Institute and the University of California Los Angeles published findings March 17, 2026, in Cell Reports Methods discussing building and testing a new computational tool for tackling massive and complex sequencing datasets. The new resource, named metapipeline-DNA, may also make sequencing data analysis more standardized across different research labs.