19-Jun-2025 Supercomputer simulations show how to speed up chemical reaction rates DOE/Oak Ridge National Laboratory Using the now-decommissioned Summit supercomputer, researchers at the Department of Energy’s Oak Ridge National Laboratory ran the largest and most accurate molecular dynamics simulations yet of the interface between water and air during a chemical reaction. Journal JACS
13-Jun-2025 LPS-treated stem cells show reduced healing in stroke therapy choose FAR Publishing Limited A new study shows that treating mesenchymal stem cells with lipopolysaccharide (LPS) shifts their energy use toward glycolysis, reducing their healing potential in stroke therapy — offering insights into improving cell-based treatments for brain injuries. Journal BIOCELL Funder Russian Science Foundation
12-Jun-2025 Molecular structure determined for efflux pumps that confer tuberculosis bedaquiline resistance University of Alabama at Birmingham The protein MmpL5 is an efflux transporter, a critical pump that helps the pathogen M. tuberculosis grow by scavenging essential iron. Unfortunately, overexpressed MmpL5 can also pump out bedaquiline — the first new turberculosis drug in over 40 years — making the bacteria drug-resistant. Diabling the efflux transporter of M. tuberculosis with an inhibitor would strike a double blow — restore microbial sensitivity to antibiotic bedaquiline and break the cycle that gathers scarce iron. Researchers have now solved the structure of MmpL4, a close homolog of MmpL5 that has the same function. Journal Nature Communications
10-Jun-2025 Excitation–inhibition balance controls synchronization in a simple model of coupled phase oscillators Osaka Metropolitan University Osaka Metropolitan University researchers provide valuable insights into the role of excitation–inhibition balance in synchronizing coupled oscillators and neurons. Journal Neural Computation
6-Jun-2025 How black wolfberry makes its antioxidant armor? Nanjing Agricultural University The Academy of Science Famed for its deep purple berries and potent antioxidant properties, black wolfberry (Lycium ruthenicum) thrives in harsh desert climates and holds significant nutritional and medicinal value. Journal Horticulture Research
3-Jun-2025 Scientists develop “mosquito STD” to combat malaria University of Maryland A University of Maryland entomologist helped develop a deadly fungus that spreads during mating to target mosquitoes that spread disease to humans. Journal Scientific Reports
28-May-2025 Study simulates pulling on athletes' jerseys to predict noncontact ACL injuries University of Kansas Researchers at the University of Kansas conducted a study in which subjects jumped in the air and a weight connected to their torso was dropped while in the air. The subjects landed on one leg and force, weight on the knee and other measures were taken. The results showed pulling an athletes' jersey from behind resulted in the most pressure on the knee. The findings are useful as contact sports have a much higher incidence of ACL injuries than others and that most such injuries occur when there is no direct contact to the knee made. They also illustrate the importance of building core strength in athletes to help prevent such injuries. Journal Scandinavian Journal of Medicine and Science in Sports
27-May-2025 Computed tomographic findings of eosinophilic enteritis in eight cats: Case series Osaka Metropolitan University An Osaka Metropolitan University-led team conducted a case series that retrospectively evaluated the contrast-enhanced computed tomography findings of eight cats with eosinophilic enteritis. Journal Veterinary Medicine and Science
27-May-2025 Association for Molecular Pathology releases series of reports defining core bioinformatics competencies for clinical diagnostic laboratories Association for Molecular Pathology Three interrelated Body of Knowledge papers outline roles and required skills for bioinformaticians with respect to molecular diagnostics, clinical bioinformatics, clinical laboratory regulation and data security Journal Journal of Molecular Diagnostics
