Today, Nature and other Nature Portfolio journals published a collection of more than 40 peer-reviewed papers marking a milestone toward researchers’ understanding of the human body in health and disease and the development of the first draft of the Human Cell Atlas (HCA). The Human Cell Atlas is an international community whose mission is to align groups engaged in creating comprehensive reference maps of all human cells — the fundamental units of life — as a basis for understanding human health and for diagnosing, monitoring, and treating disease. The Chan Zuckerberg Initiative (CZI) is one of the HCA’s first and largest funders and provided support for a third of the papers included in this landmark release. The research papers cover an impressive variety of tissues, cell types, and organs, such as the brain, immune system, thymus, and endometrium. These papers advance scientific research by introducing novel methods and frameworks for improving the analysis, integration, and visualization of complex, high-dimensional single-cell and multi-omics datasets, enabling more accurate cell type identification, spatial mapping, and understanding of cellular heterogeneity across various biological contexts and diseases.

University Hospitals Brain Health & Memory Center is now treating patients with KISUNLA™ (donanemab), a Food and Drug Administration-approved medication for the treatment of Alzheimer’s disease. UH is the only health system in Northeast Ohio currently offering these infusion treatments. Donanemab has shown promise in clinical trials and may be a treatment option for patients with mild cognitive impairment and mild dementia due to Alzheimer’s disease.

A new study by researchers at the University of Galway and the University of Limerick suggests that electrical stimulation might be essential for tendons to maintain their health, offering fresh possibilities in tendon repair and regeneration. 

Small groups of patients can now yield reliable results, Rutgers Health study finds.

In work published today in Nature, researchers’ structural insights help reveal weak spot in malaria’s plan of attack which could help guide vaccine design. Contributors hailed from Fred Hutch, the Scripps Research Institute, the University of Copenhagen and The University of Texas Health Science Center at San Antonio, as well as the Tanga Research Centre, the Infectious Disease Research Collaboration in Uganda, and the University of California, San Francisco.