In a study involving data from thousands of people, the risk of a new coronary heart disease diagnosis was statistically associated with bloodstream levels of nine specific molecules that are produced by gut microbes. Danxia Yu of Vanderbilt University Medical Center, U.S., and colleagues present these findings on March 17^th in the open-access journal PLOS Medicine.

Do you ever feel mentally stuck, like you can't cope when a stressful situation hits? A healthy breakfast, exercise, and a good night's sleep might be just what you need to build psychological flexibility, and new research from Binghamton University, State University of New York, shows why that matters.

New research indicates that the long-term neurobiological impact of childhood trauma is not permanently etched onto the brain. An analysis of brain communication patterns in a group of individuals who have experienced childhood adversity shows that lifetime physical activity can reshape neural connectivity, thereby strengthening the brain’s internal communication and optimizing its response to stress. The findings from the study in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, published by Elsevier, move beyond the idea of a permanently traumatized brain, highlighting physical activity as a modifiable lifestyle factor associated with neurobiological adaptation.