Researchers led by Prof. HU Zheng from SIAT, uncovered a polyclonal origin of tumors, challenging the traditional clonal evolution theory. Using a DNA barcoding system in mouse models and genomic analysis of human colorectal samples, they demonstrated that colorectal precancers often arise from multiple distinct cellular lineages, which later transition to monoclonality as tumors progress. These findings, published in Nature, provide critical insights into the early evolution of colorectal cancer and offer new opportunities for preventing malignant transformation.

A team of Florida State University researchers led by Assistant Professor of Mathematics Bhargav Karamched has discovered that in a foraging ant’s search for food, it will leave pheromone trails connecting its colony to multiple food sources when they’re available, successfully creating the first model that explains the phenomenon of trail formation to multiple food sources.

The Department of Energy's Quantum Computing User Program at the Oak Ridge Leadership Computing Facility is releasing a Request for Information to understand the latest in quantum computing hardware, software tools and user engagement.