The Horner–Wadsworth–Emmons (HWE) reaction is commonly used in organic chemistry to synthesize conjugated aldehydes. However, traditional HWE reaction methods sometimes have inconsistent (E)- and (Z)-selectivity, and (E)-isomers of conjugated carbonyl compounds are important for the synthesis of hynapene analogues, which have anti-cancer properties. Researchers have developed a new HWE reaction using a Weinreb amide–type HWE reagent, featuring high robustness, scalability, and (E)-selectivity. Additionally, its key intermediate can be isolated and is exceptionally stable.

President of Mount Sinai Fuster Heart Hospital given top honor for his contributions to the understanding and treatment of atherosclerosis

Continuous positive airway pressure, or CPAP, therapy can improve the lives of people with obstructive sleep apnea, but nearly half of adults with CPAP machines fail to adhere to a regular regimen of CPAP use. A new University of Arizona Health Sciences study published in the American Journal of Respiratory and Critical Care Medicine found that peer support improved CPAP adherence and patient satisfaction, which can improve sleep and overall health.