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Updates every hour. Last Updated: 11-Sep-2025 15:11 ET (11-Sep-2025 19:11 GMT/UTC)
A landmark study has revealed how inherited genetic variants, known as germline variants, play a critical role in the progression of cancer.
The research, conducted by a global consortium of scientists, including Kathleen J. Imbach and contributors from the Josep Carreras Leukaemia Research Institute (IJC), offers new insights into how these genetic factors influence molecular processes across a wide range of cancer types.
David A. Drew, PhD, of the Clinical & Translational Epidemiology Unit and Division of Gastroenterology at Massachusetts General Hospital, is the corresponding author of a paper published in Cellular and Molecular Gastroenterology and Hepatology, “Droplet vs. Picowell: Considerations for single-cell transcriptomic profiling of human colon biopsies