A group of researchers including scientists of the Earth-Life Science Institute (ELSI) at Institute of Science Tokyo have uncovered a surprising role for calcium in shaping the building blocks of life. Their study reveals that calcium ions help determine the molecular "handedness" (chirality) of tartaric acid polymers—an essential feature of biological molecules like DNA and proteins. This discovery sheds light on how life's uniform molecular structures may have first emerged on early Earth. In a twist on traditional theories, the researchers suggest that simple polyesters, in addition to peptides or nucleic acids, could have adopted this crucial trait on early Earth, offering a fresh perspective on life’s chemical origins.

The current capabilities of large language models already qualify them to advise students on medical ethics

Messenger RNA can travel between different types of stem cells through tunnel-like structures, as revealed by a new study. By studying interactions between mouse and human stem cells, they discovered that this RNA transfer can reprogram human cells to an earlier developmental state. This groundbreaking finding not only sheds light on an underexplored form of cellular communication but also suggests promising applications in regenerative medicine without using artificial genetic modifications or external chemicals.

Kyoto, Japan -- Six years before the start of the COVID-19 pandemic, an Ebola outbreak in West Africa had people fearing the possibility of a global outbreak. This was the first time many had ever heard of the virus, but since it was first identified in 1976, there have actually been more than 20 serious Ebola incidents. Thankfully, none of them had the global reach of the coronavirus.

Ebola has not been eradicated, however. This deadly virus, which causes severe hemorrhagic fever in humans and has a fatality rate of about 50%, is still at large and could thus still cause a major outbreak, unless further research finds an effective solution.

A major challenge lies in the virus' structure and regulatory mechanisms, which have remained largely unclear. In particular, scientists have long struggled to fully understand its nucleocapsid, the protein shell that plays an important role in genome replication and transcription.