Leaked tritium revealing the mechanism of radioactive cesium flow from Fukushima Daiichi to the ocean
Peer-Reviewed Publication
Updates every hour. Last Updated: 31-Oct-2025 23:11 ET (1-Nov-2025 03:11 GMT/UTC)
In their recent paper in Nucleic Acids Research, Pandey et al. report that the key effect of nucleoside supplementation is not a general boost in all DNA components—but a specific balancing act involving T (thymidine).
Stevens–Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) are life-threatening diseases requiring new effective treatments. Our group previously identified necroptosis as a key form of cell death in lesional skin. To develop novel therapeutics that inhibit necroptosis, we established a screening system using a compound library of over 200,000 molecules. Experiments in SJS/TEN model cells and mice demonstrated that the identified inhibitor effectively suppresses necroptosis, suggesting its therapeutic potential for SJS/TEN.