Cellular “scaffold” key to first successful implant of myoblasts onto healthy muscle
Peer-Reviewed Publication
Updates every hour. Last Updated: 17-Jun-2025 06:09 ET (17-Jun-2025 10:09 GMT/UTC)
Tokyo, Japan – Researchers from Tokyo Metropolitan University have developed a way to treat ageing-related muscular atrophy using regenerative medicine. Conventional methods to implant myoblasts, precursors to muscle fiber, required prior scarring for the new cells to graft properly. By adding extracellular matrix (ECM) fluid into the implant, the team successfully grafted myoblasts onto healthy muscle in mice. Their technique opens the way for using implantation to treat unscarred muscle atrophied by ageing.
Three innovative design techniques substantially enhance wireless transmitter performance and can boost power efficiency and elevate data rates concurrently, as reported by the researchers from Science Tokyo, Japan. This effectively aligns with the growing demand for speed and efficiency, accelerating the widespread deployment of wireless devices. This enables synergistic operation of wireless electronic devices and better quality of modern life.Three innovative design techniques substantially enhance wireless transmitter performance and can boost power efficiency and elevate data rates concurrently, as reported by the researchers from Science Tokyo, Japan. This effectively aligns with the growing demand for speed and efficiency, accelerating the widespread deployment of wireless devices. This enables synergistic operation of wireless electronic devices and better quality of modern life.
Kyoto, Japan -- Asteroids that orbit close to the Earth inevitably cause us some anxiety due to the even remote possibility of a collision. But their proximity also offers ample opportunities to learn more about the universe. Ryugu, a 900-meter diameter asteroid in the Apollo belt, has recently proven useful in our search for signs of life's precursors elsewhere in our Solar System.
A team of researchers at Kyoto University have found evidence of salt minerals in samples recovered from Ryugu during the initial phase of Japan's Hayabusa2 mission. The discovery of these deposits, containing sodium carbonate, halite, and sodium sulfates, suggest that liquid saline water once existed within a parent body of Ryugu.
Before examining the samples, the team expected that sample grains returned from the asteroid might contain substances not generally found in meteorites. They anticipated that these could be highly water-soluble materials, which readily react with moisture in Earth's atmosphere and are difficult to detect unless examined in their pristine state as preserved in the vacuum of space.
Porous organic crystals with superior properties as CO2 adsorbents were created by researchers at Institute of Science Tokyo. Owing to the novel 2.5-dimensional skeleton, the materials feature ultrahigh-density amines. The covalently-bonded microporous skeleton and high crystallinity realize fast CO2 adsorption and high thermal stability. Their low adsorption heat, only one-fourth of the current amine scrubbing method, and their light-elemental nature can reduce the cost for CO2 separation from flue gases.
A recent study led by Associate Professor Takuya Yamamoto and Researcher May Nakajima-Koyama has revealed that maintaining a delicate balance between interferon-gamma (IFN-γ) and extracellular signal-regulated kinase (ERK)/mitogen-activated protein kinase (MAPK) signaling is essential for preserving the intestinal stem cell population during aging. By comparing young and aged mouse intestinal tissues, the researchers uncovered critical insights into the interplay between these signaling pathways in supporting stem cell maintenance over time.
Biological motors, which aid microorganism movement in fluids, are composed of two components—the rotor and stators. Despite much research, the exact molecular mechanism underlying stator function is yet unclear. In a new study, researchers from Nagoya Institute of Technology analyzed the flagellar motor in Vibrio alginolyticus using cryo-electron microscopy and described how sodium ion flow through stators underlies stator function. Understanding biological motors better could lead to the development of efficient microscopic machines.