A controlled/“living” click polymerization method developed by researchers at Institute of Science Tokyo and Nagoya University enables precise chain-growth of AB-type monomers—traditionally limited to step-growth processes—by leveraging copper-catalyzed azide–alkyne cycloaddition. The approach achieves well-defined polymers with narrow dispersity and enables the bidirectional synthesis of ABA-type block copolymers, offering a powerful new strategy for constructing functional macromolecular architectures from a wide range of monomers.

Childhood maltreatment increases the risk of long-term health and psychological issues, but how it alters children’s development at a biological level remains unclear. In a recent study, researchers from Japan investigated both biological aging and social attention in maltreated preschoolers. Using DNA methylation markers and eye-tracking data, researchers found that abuse accelerates cellular aging and disrupts a child’s attention to people’s eyes—two independent pathways linked to emotional and behavioral difficulties.

A new palladium-loaded amorphous InGaZnO_x (a-IGZO) catalyst achieved over 91% selectivity when converting carbon dioxide to methanol, report researchers from Japan. Unlike traditional catalysts, this system leverages the electronic properties of semiconductors to generate all the species necessary for the conversion reaction. This study demonstrates novel design principles for sustainable catalysis based on electronic structure engineering.

Indium gallium zinc oxide (IGZO)-based displays suffer from instability caused by atomic-scale defects. Now, a new study provides the first insights into these instabilities in single-crystal IGZO. Researchers grew high-quality IGZO single crystals and uncovered how oxygen vacancies and structural disorder create unwanted electronic states—details that were unclear in previous studies using amorphous IGZO samples. These findings could guide the development of more stable and longer-lasting displays for smartphones, televisions, and other devices.

A research group led by Dr. Keisuke Obara, Dr. Kento Yoshioka, and Professor Yoshio Tanaka from the Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Toho University, has uncovered important details about how platelet-activating factor (PAF)—a powerful molecule involved in inflammation and allergic reactions—triggers contractions in the smooth muscles of the esophagus. Their findings could pave the way for new treatments targeting gastrointestinal symptoms associated with allergies, asthma, and anaphylaxis.