A pioneering study conducted by Professor Fangyin Dai's team at Southwest University introduces a novel strategy for bone defect repair using flat silkworm cocoon (FSC) fiber scaffolds functionalized with magnesium ions (Mg²⁺). This innovative material not only addresses the limitations of traditional silk-based scaffolds but also exhibits superior immunomodulatory and osteogenic properties, thereby opening new avenues for cost-effective, sustainable, and highly efficient solutions in orthopedic regenerative medicine.

The findings reveal that the lattice constants of these compounds decrease with increasing pressure, with more significant changes observed when anions are substituted from Cl to I.

This paper introduces WisdomBot, a novel Large Language Model (LLMs) designed specifically for education. By incorporating educational theories and specialized knowledge, WisdomBot aims to overcome the limitations of general LLMs in educational domain. The model utilizes self-instructed knowledge concepts and instructions guided by Bloom’s Taxonomy for training. Additionally, during inference, it employs local knowledge base retrieval augmentation and search engine retrieval augmentation to enhance accuracy and professionalism of its responses. Experiments demonstrate the effectiveness of WisdomBot in generating reliable and professional educational content.

Researchers have developed a novel approach to enhance the generative capabilities of Large Language Models (LLMs) through the integration of Retrieval-Augmented Generation (RAG), specifically designed for complex financial tasks.

Advancements in life sciences have heightened public understanding of dermatology, emphasizing the importance of photoprotection against UV and visible light, including blue light (BL). This review, from the perspective of skin photobiology, systematically organizes the impact of BL on the skin, its mechanisms of action, and scientific protective measures. The research team at MISTINE presents in this article the results of their skin photobiological sun protection system in the field of BL research. The study of red rice extract has become a core active component in the field of skin photobiology. BL, part of sunlight from 400 to 500 nm, penetrates deeply into skin, causing oxidative stress, pigmentation, and matrix degradation, leading to hyperpigmentation, dullness, uneven tone, and wrinkles. This study investigates the clinical manifestations of BL-induced skin photodamages, as well as the underlying biological mechanisms and proposes rational BL protection strategies. The skin photobiological sun protection system proposed by MISTINE not only focuses on ultraviolet rays but also delves deeper into the photobiological effects of BL on the skin, providing more comprehensive protection for the skin.

Researchers from DICP developed a highly sensitive proteomics method called peptide-centric local stability assay (PELSA), which enables the simultaneous identification of ligand-binding proteins and their binding sites in complex systems. PELSA is broadly applicable to diverse ligands including metabolites, drugs, and pollutants.

Researchers have developed a new aluminosilicate zeolite, ZMQ-1, which features a unique intersecting meso-microporous channel system that is expected to enhance catalytic processes in the petrochemical industry.

Researchers from Osaka Metropolitan University have developed nanofluidic devices capable of manipulating single nanoscale objects, including DNA, nanoparticles, proteins, and small molecules in solution. They introduced "nanofluidic manipulation," enabling precise nanoscale control. In a review article, they highlighted advancements, challenges, and the transformative potential of this emerging field for integrating scientific fields and driving innovation.

In a surprising development in the field of robotics, researchers have discovered that small modifications to a robot’s body mass and ball size can significantly enhance its balancing abilities.

Microwave dielectric ceramics, as the core component of fabrication of passive electronic devices, are widely used in numerous fields such as filters, dielectric antennas, and microwave communications . For high-frequency communication, microwave dielectric ceramics with low relative permittivity (ε_r) are preferable due to their ability to decrease signal latency and facilitate the manufacturing of passive components. Additionally, microwave dielectric ceramics that are ideal for making passive components should have a temperature coefficient of resonance (τ_f) as near to zero as feasible and a high quality factor (high Q×f, that is, low dielectric loss tanδ = 1/Q). Vanadium-based zircon ceramics hold potential application prospects in the next generation of wireless communications due to their low dielectric constant and adjustable temperature coefficient of resonant frequency at microwave frequencies. However, achieving ultra-low dielectric loss still poses a significant challenge.