Predictive model developed at São Paulo State University (UNESP) helps identify tumor biomarkers of this metabolic syndrome characterized by acute weight loss and muscle wasting.

In laboratory mice, the hormone easily bought from pharmacies and widely consumed as a supplement aggravated Crohn’s disease and ulcerative colitis, depending on the animal’s gut microbiota profile, according to a study by researchers at the University of São Paulo.

Researchers show the importance of political skill on the part of federal research institution Fiocruz and regulatory agency ANVISA in the process that resulted in the signature of an agreement with pharmaceutical company AstraZeneca in mid-pandemic.

The most comprehensive sequencing to date of the genomes of the Leatherback and Green sea turtles shows they are mostly identical. An article in PNAS helps scientists understand how the group has evolved and provides ideas for conservation strategies.

In a study with 116 participants, researchers at the Federal University of São Paulo evaluated the genetic material contained in extracellular vesicles possibly secreted by brain tissue. The analysis pointed to patterns of microRNA expression associated with depression, anxiety and ADHD.

Researchers observed the behavior and brain structures of mice after they developed addiction to cocaine, noting more agitation and brain activation associated with a specific environment.

This was the main finding of a study involving rats conducted by Brazilian researchers. Mortality was 29% higher for fetuses exposed to a synthetic compound that acts on the brain in a similar manner to natural cannabinoids. Respiratory control and CO2 sensitivity, which influence sudden infant death syndrome, were also altered.

During the peak of the Covid-19 pandemic, a constant public fear was the rise of a new variant of the disease. Among the countless possibilities of a SARS-CoV-2 viral mutation, some were really alarming, such as Omicron, Delta, and Gamma. The strains with greater virulence and ability to invade the immune system are defined as variants of concern (VOCs), since they also have the potential to overwhelm the health system, increasing the number of admissions to intensive care units (UTIs). Recently published in the Intensive Care Medicine journal, a new study led by the D'Or Institute for Research and Education (IDOR) used Big Data analysis techniques to compare the profile of patients admitted to Brazilian ICUs during the dominance of different VOCs.

Concern about the mental health of hospital professionals has been increasing in recent years, and when, in early 2020, the Covid-19 pandemic was declared and rapidly spread, there was a large increase in the overload of workers in Intensive Care Units (ICUs). Given this, researchers from the D’Or Institute for Research and Education (IDOR) and other national institutions assessed the prevalence and extent of psychological disorders such as burnout, anxiety, depression, and post-traumatic stress disorder (PTSD) in pediatric ICUs (PICUs) health professionals. The study was published in the scientific journal Pediatric Critical Care Medicine and selected as the Feature Article and Editor’s choice of the month, receiving a specific editorial.