8-Jan-2020 Brazilian scientists unveil chemotherapy resistance mechanism related to p53 mutation Instituto Nacional de Ciência e Tecnologia de Biologia Estrutural e Bioimagem (INBEB) Peer-Reviewed Publication Brazilian study uncovered an anticancer chemotherapy resistance mechanism related to amyloid aggregation of mutant p53. The research was conducted in cells derived from glioblastoma, a super aggressive brain tumor, and in living cells. The results open up new opportunities for the development of more effective therapies against cancer. Journal iScience
6-Jan-2020 Jaguars could prevent a not-so-great American biotic exchange Smithsonian Tropical Research Institute Peer-Reviewed Publication In eastern Panama, canid species from North and South America are occurring together for the first time. Urban and agricultural development and deforestation along the Mesoamerican Biological Corridor might be generating a new passageway for these invasive species adapted to human disturbance. Journal Journal of Mammalogy Funder Sistema de Producción Sostenible para la Conservación de la Biodiversidad-Ministerio de Ambiente, North Carolina State University
19-Dec-2019 Asteroid collisions trigger cascading formation of subfamilies, study concludes Fundação de Amparo à Pesquisa do Estado de São Paulo Peer-Reviewed Publication Scientists have always thought about fission clusters as entirely distinct from collisional families. Now a study conducted by researchers affiliated with UNESP has shown that fission clusters may originate from collisional families in some cases. Journal Nature Astronomy Funder São Paulo State Research Support Foundation (Brazil). Geochronologic research at the MIT Isotope Lab
17-Dec-2019 Researchers create functional mini-liver by 3D bioprinting Fundação de Amparo à Pesquisa do Estado de São Paulo Peer-Reviewed Publication Technique developed at Human Genome and Stem Cell Research Center, funded by FAPESP and hosted by the University of São Paulo, produced hepatic tissue in the laboratory in only 90 days and could become an alternative to organ transplantation in future. Journal Biofabrication Funder São Paulo Research Foundation - FAPESP
17-Dec-2019 Novel genetic signature that can predict some kinds of breast cancer is identified Fundação de Amparo à Pesquisa do Estado de São Paulo Peer-Reviewed Publication The research, published in the journal PLOS Genetics, combined a study of the genes involved in retinopathy, as a model of angiogenesis, with analysis of transcriptomic gene expression profiles from public breast cancer databases. Journal PLOS Genetics Funder São Paulo Research Foundation - FAPESP
16-Dec-2019 Leafcutter ants accelerate the cutting and transport of leaves during stormy weather Fundação de Amparo à Pesquisa do Estado de São Paulo Peer-Reviewed Publication A study by researchers at the University of São Paulo's Luiz de Queiroz College of Agriculture (ESALQ-USP) in Brazil shows that leafcutter ants are capable of predicting adverse weather by sensing changes in atmospheric pressure. Journal Ethology Funder São Paulo State Research Support Foundation (Brazil). Geochronologic research at the MIT Isotope Lab
16-Dec-2019 The sympathetic nervous system can inhibit the defense cells in autoimmune disease Fundação de Amparo à Pesquisa do Estado de São Paulo Peer-Reviewed Publication Using an experimental model of multiple sclerosis, the scientists found that the sympathetic nervous system can limit the generation of effector responses by inhibiting the action of the cells that attack an antigen taken as a threat by the immune system. Journal Cell Reports Funder São Paulo State Research Support Foundation (Brazil). Geochronologic research at the MIT Isotope Lab
13-Dec-2019 The wild relatives of major vegetables, needed for climate resilience, are in danger The Alliance of Bioversity International and the International Center for Tropical Agriculture Peer-Reviewed Publication The genes that make crop wild relatives robust have the potential to make their cultivated cousins -- our food plants -- better prepared for a harsh climate future. But a series of new research papers show these critical plants are imperiled. Journal Plants People Planet
12-Dec-2019 Beyond 'shovelomics': Growing cassava in the air helps study the plant's mysterious roots The Alliance of Bioversity International and the International Center for Tropical Agriculture Peer-Reviewed Publication Scientists at the International Center for Tropical Agriculture grew cassava in the air -- using a technique called aeroponics -- to better understand the root growth of one of the world's hardiest staple crops. Journal Plant Methods
11-Dec-2019 Study to help manage shark populations in Pacific Panama Smithsonian Tropical Research Institute Peer-Reviewed Publication A study in Pacific Panama identifies 11 potential nursery areas of locally common and migratory sharks, which could support shark conservation efforts in the region. Funder Tecnología e Innovación de Panamá (SENACYT), Panalang-Union Group, Secretaría Nacional de Ciencia, Smithsonian Tropical Research Institute, Sistema Nacional de Investigación de Panamá