9-Aug-2018 A new, highly effective and selective molecule is developed to fight malaria Fundação de Amparo à Pesquisa do Estado de São Paulo Peer-Reviewed Publication In tests with mice and in vivo culture, molecule designed in Brazil was capable of killing Plasmodium resistant strains and reducing the number of parasites in the bloodstream by 62 percent without attacking cells of the host organism. Journal Journal of Medicinal Chemistry Funder Sao Paulo Research Foundation - FAPESP
7-Aug-2018 A sterile line of Aedes aegypti is developed to fight off arbovirosis Fundação de Amparo à Pesquisa do Estado de São Paulo Business Announcement In Brazil, male specimens with defective sperm are created in lab; manufacturing the transgenic mosquito in large scale could integrate coordinated strategies to control dengue, chikungunya, Zika and yellow fever epidemics. Funder Sao Paulo Research Foundation - FAPESP
6-Aug-2018 Low-protein diet during pregnancy increases prostate cancer risk in offspring Fundação de Amparo à Pesquisa do Estado de São Paulo Peer-Reviewed Publication Experiments with rats show that intrauterine protein restriction induces sex hormone imbalance, which appears to favor development of cancer in old age. The rate of prostate tumor development reached 50 percent among the old rats submitted to low-protein diet during pregnancy and lactation alike. Funder Sao Paulo Research Foundation -- FAPESP
3-Aug-2018 Each tropical tree species specializes in getting the nutrients it needs Smithsonian Tropical Research Institute Peer-Reviewed Publication Researchers looking for general patterns in the way tropical trees capture nutrients were surprised to find that every species has its own way of getting the nutrients it needs. The concept of biodiversity extends to their behavior. Journal Ecology Letters Funder HSBC Bank USA, Stanley Motta, Small World Institute Fund, Hoch Family, Smithsonian Institution, National Science Foundation, Heising-Simons Foundation
3-Aug-2018 Key gene to accelerate sugarcane growth is identified Fundação de Amparo à Pesquisa do Estado de São Paulo Peer-Reviewed Publication Brazilian researchers developed a sugarcane line with the ScGAI gene expression silenced. The modification resulted in an adequate phenotype for use in 2G ethanol production, featuring a bigger culm and more biomass. Journal Journal of Experimental Botany Funder Sao Paulo Research Foundation - FAPESP
2-Aug-2018 Study elucidates epigenetic mechanisms behind autoimmune diseases Fundação de Amparo à Pesquisa do Estado de São Paulo Peer-Reviewed Publication Brazilian researchers use an editing tool to investigate a gene that plays a key role in eliminating autoaggressive cells and controlling the development of diseases such as type 1 diabetes. In tests with mice, the disrupting of medullary thymic epithelial cells gene impaired the processing of mRNA involved in their adhesion to autoaggressive T lymphocytes. Journal Frontiers in Immunology Funder Sao Paulo Research Foundation - FAPESP
2-Aug-2018 Tropical forest seeds use three strategies to survive Smithsonian Tropical Research Institute Peer-Reviewed Publication From tiny banana seeds to giant coconuts, it's tough for seeds to survive in tropical soils where they are under constant attack by fungi, bacteria, insects and animals. By understanding how seeds defend themselves, tropical biologists contribute to reforestation, crop management and sustainable agriculture in the tropics. Journal Ecology Funder U.S. National Science Foundation and Simons Foundation
30-Jul-2018 Study shows how Oropouche virus replicates in human cells Fundação de Amparo à Pesquisa do Estado de São Paulo Peer-Reviewed Publication Results described in PLOS Pathogens point to potential targets worth exploring in effort to halt infection by the emerging virus, which is transmitted by the C. paraensis midge. Oropouche's strategy of 'hijacking' the Golgi complex in order to replicate itself has never been described before, state the researchers. Journal PLOS Pathogens Funder Sao Paulo Research Foundation - FAPESP
26-Jul-2018 New two-dimensional material could revolutionize solar fuel generation Fundação de Amparo à Pesquisa do Estado de São Paulo Peer-Reviewed Publication International group of researchers including Brazilian scientists obtain from hematite a new material with application as a photocatalyst, christened 'hematene.' The three-atom thick hematene is a ferromagnetic material, as opposed to the iron ore from which it was created from. Journal Nature Nanotechnology Funder Sao Paulo Research Foundation - FAPESP
24-Jul-2018 Research shows how the Little Ice Age affected South American climate Fundação de Amparo à Pesquisa do Estado de São Paulo Peer-Reviewed Publication For the first time, scientists reconstruct the rainfall distribution in Brazil during the climate changes that marked the Middle Ages using isotopic records from caves. Funder Sao Paulo Research Foundation - FAPESP