This article reports on a new study published in Engineering that presents a reliability-based code calibration procedure for pultruded glass fiber-reinforced polymer I-section beams. The research focuses on determining optimal partial safety factors for web-crippling under end-two-flange and interior-two-flange loading cases, contributing to more reliable design guidelines for these materials in civil engineering applications.

Researchers from China Agricultural University and Jiangsu University have developed a new control mechanism for electric tractors. Their study, published in Engineering, details a system that enhances operational quality and energy efficiency through real-time data interaction and collaborative task management. The innovations include a high-performance controller and a hierarchical real-time operating system that optimize tractor performance.

An expert consensus addresses the critical issue of instrument separation during root canal therapy, a common complication that jeopardizes treatment success.

After flu infection, memory T cells in the lung migrate to nearby lymph nodes via CCR5, forming a long-lasting immune reservoir. This discovery reveals a backup strategy for lung immunity and may inform future vaccine design.

A Chinese research team has shown how a climate shift from wet to sub-humid conditions 167 million years ago reshaped East Asia’s landscapes, driving an increase in biodiversity in the Yanliao Biota. Published in National Science Review, the study highlights how varied habitats drove the evolution of early mammals, dinosaurs, and insects in the North China Craton.

This study introduces a variational quantum metrology scheme based on Loschmidt echo and experimentally demonstrates its quantum-enhanced characteristic, providing a promising framework for quantum metrology across diverse practical quantum systems.

Oocyte quality is the key limiting factor of female fertility. However, compared with other species, the research and understanding of human oocyte quality and human reproductive health is limited. This review will highlight the current understanding of the physiological and pathological factors on human oocyte quality and discuss the potential treatments. In physiology, researchers discuss the regulation of the hypothalamic-pituitary-gonadal axis, granulosa cells, key subcellular structures, maternal mRNA homeostasis, the extracellular matrix, maternal microenvironment, and multi-omics resources related to human oocyte quality. In pathology, they reviewed the hypothalamic-pituitary-gonadal defects, ovarian dysfunction including premature ovarian insufficiency and polycystic ovary syndrome, human oocyte development defects, and aging. Furthermore, they outline the emerging scientific prospects and challenges for future mechanisms exploration and clinical treatment. This review seeks to deepen our understanding of the mechanisms regulating human oocyte quality and to provide novel insights into clinical female infertility characterized by defects in oocyte quality and oocyte development.

Acute stroke in pregnancy and puerperium (ASPP) can be life-threatening and clinically difficult to manage. A new study by researchers in China presents a comprehensive research protocol to investigate the potential risk factors of ASPP, risk of recurrent strokes during future pregnancies and impact of ASPP on the development of offspring. This research provides a robust framework to gain vital insights into the maternal and neonatal outcomes associated with ASPP.

Delayed complications following stereotactic radiosurgery (SRS) for brain arteriovenous malformations (AVMs) are rare and poorly understood. This case report describes a patient who developed cyst formation ten years after SRS, which later progressed to a chronic encapsulated expanding hematoma (CEEH). The study highlights a likely pathophysiological link between cyst formation and CEEH and emphasizes the importance of complete surgical removal to prevent recurrence and ensure long-term resolution of such late-onset complications.