Carrier-free peptide–daunorubicin–small interfering RNA nanoassembly for targeted therapy of acute myeloid leukemia
Peer-Reviewed Publication
Updates every hour. Last Updated: 23-Dec-2025 14:11 ET (23-Dec-2025 19:11 GMT/UTC)
A research paper by scientists at Beijing Institute of Technology presented a carrier-free tumor-suppressing peptide–daunorubicin–siRNA (PDR) nanoassembly.
The research paper, published on Nov. 5, 2025 in the journal Cyborg and Bionic Systems.A single-dose CRISPR-CasRx nanotherapy targeting a host enzyme reduces SARS-CoV-2 viral load and promotes alveolar repair in a hamster model of long COVID, offering a promising strategy for treating post-acute lung damage.
The rational design of platinum-based electrocatalysts with optimized metal-support electronic interactions remains a fundamental challenge in achieving atom-efficient hydrogen evolution reaction (HER).
Scientists have developed an innovative "sulfur-for-oxygen exchange" method to synthesize a porous Fe₂(MoO₄)₃/CoMoO₄ heterojunction electrocatalyst. This material demonstrated exceptional oxygen evolution reaction (OER) performance, requiring only 244 mV of overpotential to achieve a current density of 10 mA·cm⁻² – significantly outperforming commercial benchmarks. Furthermore, it exhibited outstanding stability, operating continuously for over 100 hours. This breakthrough paved the way for scalable, cost-effective green hydrogen production.
This research develops PPCZ@Gauze, an innovative nanoengineered dressing for infected wounds. Utilizing biosafe components (phytic acid, ε-polylysine, curcumin, Zn²⁺), it enables sustained release for synergistic antibacterial, anti-adhesive, and angiogenic effects. In vitro and in vivo studies confirm accelerated healing, reduced infection, and minimized tissue adhesion. Cost-effective, scalable, and biocompatible, it's ideal for clinical treatment of infected wounds.
CS/Ti3C2Tx/Co@CNTs composite could obtain the minimum reflection loss (RLmin) of -55.01 dB at the thickness of 3.4 mm and the effective absorption bandwidth (EAB) could reach 9.07 GHz. It should be emphasized that the average density of CS/Ti3C2Tx/Co@CNTs is only 0.03 g/cm3. The electrostatic self-assembled CS/Ti3C2Tx/Co@CNTs composites behaved the excellent conductive loss, polar loss and the impedance matching.
A research paper by scientists at Chinese Academy of Sciences presented a magnetically actuated soft electrode (MSE) with precise navigation, adaptive attachment, and high-fidelity signal acquisition.
The research paper, published on Oct. 24, 2025 in the journal Cyborg and Bionic Systems.A novel fiber optic sensing platform captures real-time bubble dynamics during hydrogen evolution, revealing how bubble growth and detachment impact catalyst performance. This breakthrough bridges interfacial gas behavior with electrochemical efficiency, offering new strategies for green hydrogen optimization.
Researchers have introduced a statistical method that allows accurate forest monitoring using satellite images with missing data. The hybrid estimator works directly with flawed data, bypassing the need for complex and uncertain data repair processes. This approach achieved over 90% sampling precision, meeting national forest inventory standards, and performed as well as techniques requiring complete satellite imagery. This provides a cost-effective way to leverage decades of archived satellite data for reliable forest and carbon stock assessment, supporting vital climate and conservation efforts.