Teams engineer microporous new CO₂-activated carbon material—Enabling energy-efficient separation of critical fluorinated gases
Peer-Reviewed Publication
Updates every hour. Last Updated: 16-Nov-2025 17:11 ET (16-Nov-2025 22:11 GMT/UTC)
Long COVID continues to affect millions, with symptoms that mirror those of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). This research highlight reveals that both conditions share common roots in cellular oxidative stress and immune dysfunction, potentially leading to long-term brain damage. It proposes that ME/CFS is a progressive neurodegenerative disorder and could serve as a useful model for understanding brain aging, energy failure, and the lasting neurological effects of viral pandemics.
This case report highlights an unusual presentation of Adult Still’s Disease (ASD), a rare systemic inflammatory disorder, in a 26-year-old woman who exhibited atypical skin symptoms without classical febrile patterns. ASD is typically characterized by spiking fevers, arthritis, and an evanescent salmon-pink rash, but the patient instead presented with widespread urticarial and erythematous plaques accompanied by pruritus and angioedema. These lesions initially led to misdiagnosis and ineffective treatments for conditions like scabies and infectious diseases. Laboratory tests revealed hallmark features of ASD, including leukocytosis with neutrophilia, elevated C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR), hyperferritinemia, and negative rheumatoid factor (RF) and antinuclear antibodies (ANA). Despite the absence of classical skin findings, the patient fulfilled Yamaguchi’s diagnostic criteria for ASD. The diagnosis was ultimately confirmed based on clinical features and lab results, without requiring skin biopsy. Treatment with corticosteroids and methotrexate led to significant clinical improvement. This case emphasizes the diagnostic challenges posed by atypical cutaneous manifestations of ASD and highlights the importance of considering ASD in the differential diagnosis of persistent systemic symptoms with non-specific dermatologic signs. Early recognition and appropriate management are crucial to prevent complications and improve outcomes. The report underscores the need for heightened clinical awareness of ASD’s diverse presentations, particularly in dermatological settings, and supports the use of Yamaguchi’s criteria in guiding diagnosis even in atypical cases. It also reinforces the effectiveness of methotrexate as a steroid-sparing agent in managing persistent ASD symptoms.
This article reviews recent advances in flexible electrochromic (EC) devices for wearable electronics, offering in-depth insights into material innovations, device structures, performance metrics, and practical applications. It also highlights the key challenges and future prospects of flexible EC technologies, aiming to bridge the gap between materials research and real-world implementation in smart wearable systems.
Objective
Colorectal cancer (CRC), a common malignant tumor of the digestive tract, poses a worldwide threat to human health. Methods: This study conducted a narrative literature review to assess and provide perspectives on the evolving understanding of dietary nutrients and one-carbon metabolism in the context of colorectal cancer.
Results
Certain nutrients can serve as precursor (methionine and serine) or cofactor (B vitamins) for one-carbon (1C) units, participating in 1C metabolism through a network of interrelated biochemical pathways that involve the transfer of 1C units. 1C metabolism, in turn, affects tumor cell fate through several mechanisms such as nucleotide synthesis, epigenetic modifications, redox homeostasis, and the interaction with gut microbiota, all of which are implicated in the pathogenesis and progression of CRC.
Conclusions
A deeper understanding of the intricate relationships between the three offers new insights into the mechanism of 1C metabolism in the development of CRC, the role of diet in modulating one-carbon metabolism and potential therapeutic interventions for cancer.
Elsevier and Ruijin Hospital, Shanghai Jiao Tong UniversitSchool of Medicine, have deepened their cooperation to launch an interdisciplinary academic journal LabMed Discovery (LMD) with international reach.
The research output in China continues to grow exponentially, leading to a significant rise in both article volume and quality. Recognizing the importance of Chinese research and serving thiscommunity, Elsevier has recently forged a long-term partnership with Shanghai Jiao Tong University (SJTU) -- one of China's top university and hospital institutions. The collaboration was formally celebrated at Ruijin Hospital during STJU’s Medicine-Engineering Interdisciplinary Journal Alliance launch ceremony, which highlighted the importance of interdisciplinary research in medicine and engineering.