A new study in Engineering introduces the Machine Learning on Blockchain (MLOB) framework. This innovation combines machine learning and blockchain technology to boost computational security in engineering. It addresses the shortcomings of existing methods that overlook computational security. Tests show it improves security, maintains accuracy, and has potential for real-world applications.

A study published in Engineering offers a new network dynamic approach for evaluating aeroengine performance. This method addresses the limitations of traditional evaluation methods, providing a more comprehensive and accurate way to assess aeroengines, which is crucial for flight safety and the development of related engineering fields.

New research published in Engineering by Ju-Hyung Kim and Yail J. Kim explores the behavior of reinforced concrete beams strengthened with CFRP and UHPC under thermocyclic loading. Through experiments and analysis, the study examines aspects like uncertainty, hysteresis, and pinching mechanisms. The findings, including a proposed performance degradation factor, provide useful information for engineers working on building structures to withstand multi-hazard situations.

A new review in eGastroenterology explores how long non-coding RNAs (lncRNAs) regulate key metabolic pathways in metabolic dysfunction-associated steatotic liver disease (MASLD) and fibrosis. These findings suggest that lncRNAs could serve as novel therapeutic targets for liver disease, addressing an urgent need for effective treatments.

Tsinghua University Press announces the 2025 Carbon Future Young Investigator Award.

This study presents an integrated study combining global proteomics, lactylome, and genome-wide RNA sequencing to elucidate the role of lactylation throughout postnatal heart development. They demonstrate a remarkable increase in non-histone lactylation levels as early from 1 week (1 w) to 6 weeks (6 w) postpartum and remained elevated from 6 months (6 m) onwards. However, the histone lactylation showed the opposite trend.In particular, histone 4 lysine 12 lactylation (H4K12la) acts as a pivotal upstream regulatory element in the early postnatal mouse heart, from 1 w to 6 w postpartum. These findings strongly suggest a significant connection between lactylation and postnatal cardiac development and highlight its involvement in gene expression regulation, thus offering potential mechanisms for targeting heart diseases.

Quantum dot light-emitting diodes (QLEDs) have made rapid progress in luminescence, efficiency, and stability, making them promising candidates for displays and solid-state lighting applications. However, achieving high-performance QLEDs with high color purity remains a persistent challenge, particularly red QLEDs, thus limiting the popularity of ultra-high definition devices. Recently, Soochow University, in collaboration with Macau University of Science and Technology and other research institutes, reported a facile high-temperature successive ion layer adsorption and reaction (HT-SILAR) strategy for the growth of high-quality, large-particle, alloyed red QDs. These QDs exhibit a near-unity photoluminescence quantum yield (PLQY), and narrow emission with a full width at half maximum (FWHM) of 17.1 nm. As a result, a record external quantum efficiency (EQE) of 38.2%, luminance over 120,000 cd m⁻², and exceptional operational stability T₉₅ (tested at 1,000 cd m⁻²) of 24,100 hours were achieved for QLEDs. This work opens new avenues for synthesizing high-quality QDs with high color purity and was published in Science Bulletin.

A research team led by Zhengtao Yu introduces the Element Relational Graph-Augmented Multi-Granularity Contextualized Encoder (ERGM) for document-level event role filler extraction, outperforming baseline models and effectively capturing dependency relationships in extensive experiments on the MUC-4 benchmark.

Imagine a world where worms can hear. While it may sound like science fiction, researchers at the University of Michigan have discovered that the nematode C. elegans, a commonly studied model organism, is capable of sensing and responding to airborne sound. This groundbreaking finding challenges the long-held belief that hearing is exclusive to vertebrates and certain arthropods.

The study, published in the Biophysics Reports reveals that C. elegans exhibit a behavior called phonotaxis, where they move away from the source of sound. This response is dependent on the frequency and size of the sound source, suggesting that the worms are sensitive to sound pressure gradients rather than absolute sound pressure levels.

So, how do these microscopic creatures perceive sound? The answer lies in their skin. When airborne sound waves cause the worms’ external cuticle to vibrate, it activates specialized mechanosensory neurons called FLP and PVD. These neurons, located in the worms’ head and tail regions, respectively, respond to the vibrations by triggering avoidance behavior.

Further investigation revealed that the neurotransmitter acetylcholine (ACh) is not required for this auditory transduction process. Instead, a specific type of nicotine acetylcholine receptor (nAChR) called DES-2/DEG-3 plays a crucial role in converting sound waves into neural signals.