Lipidome and proteome insights into Mariana Trench snailfish adaptation to the Hadal Zone
Peer-Reviewed Publication
Updates every hour. Last Updated: 1-May-2025 02:08 ET (1-May-2025 06:08 GMT/UTC)
Through lipidomic and proteomic analyses, this study reveals how the Mariana Trench snailfish adapts to extreme deep-sea conditions. Findings highlight the fish’s unique lipid regulation, energy storage, and antioxidant mechanisms that enable survival under high pressure and low temperatures.
People with hip osteoarthritis are unable to activate their muscles as efficiently, irrespective of strength
The 101 Plan is a significant initiative launched in December 2021 to enhance computer science education in top Chinese universities. The plan focuses on revitalizing classroom teaching and addresses the need for updated curriculum in the Information Age. It emphasizes the development of core courses, textbooks, practice platforms, and faculty training. This article presents the plan’s organization, progress, and future plans.
The team proposed to estimate the amplified effect of popular nodes on each node's representation, and intervene the effect after each graph convolution.
In China, the real-world effectiveness and safety of Janus kinase 1 (JAK1) inhibitors for moderate-to-severe atopic dermatitis (AD) are of significant interest due to the approval of upadacitinib and abrocitinib in the country. Despite their demonstrated efficacy in clinical trials, there is a scarcity of real-world data, particularly pertaining to Asian demographics. Addressing this gap, a single-center, 24-week prospective study was undertaken at Xiangya Hospital to evaluate the practical application of abrocitinib and upadacitinib in a Chinese cohort of AD patients.
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