Oral squamous cell carcinoma (OSCC) progresses from seemingly benign preneoplastic lesions, but understanding the epigenetic triggers for this transition remains limited. 

Satellite constellation has been applied in communication, reconnaissance, navigation, and other space missions, such as GPS, Glonass, Beidou, Starlink, etc. With the rapid development of Low Earth Orbit (LEO) constellations, mega constellation will inevitably become an important means of Earth observation and a key point in the development of future satellite technology. The configuration optimization design of LEO observation mega constellation in complex space environment is a nonlinear problem that is difficult to solve analytically. During the development, constellation design principles have shifted from the uniform coverage requirement to application requirements. However, previous method cannot provide solutions to constellation configuration optimal design based on high-precision orbital propagation.

Carbon Future announced the awardees of the 2025 Carbon Future Young Investigator Award.

Artificial intelligence (AI) is rapidly reshaping the landscape of precision medicine, enabling a new era of biomarker discovery and personalized immunotherapy. A review, led by Dr. Xi Wei from the Department of Diagnostic and Therapeutic Ultrasonography at Tianjin Medical University Cancer Institute & Hospital, summarizes how AI is transforming three critical domains—immunogenomics, radiomics, and pathomics—into powerful engines for optimizing cancer treatment. The manuscript offers a comprehensive overview of how these AI-integrated disciplines are revolutionizing our understanding of tumor biology and immunotherapy response.

A new study has mapped the complex behavior of liver macrophages after acute injury, revealing how these immune cells rapidly shift roles to clear debris and promote healing. By tracking macrophages in mouse models, researchers have laid the groundwork for developing therapies that could target specific macrophage types to speed liver repair.

Y₂MgTiO₆(YMT)-based ceramics have become core candidates for high-frequency electronic devices such as millimeter-wave communications due to their high dielectric constant (ε_r), ultra-high quality factor (Q×f) and low dielectric loss. However, most of the existing studies focus on the ion doping effect at a single scale (such as lattice parameters or macroscopic properties), and the structure-activity relationship between atomic bonding, lattice distortion, phonon behavior and dielectric properties has not yet been fully revealed, especially the regulation law of the coupling mechanism of chemical bonding and lattice vibration on doped ions is still theoretically blank. This limits the design and performance control of high-performance microwave dielectric ceramic materials.

A research paper by scientists at Peking University Third Hospital presented a study on the regulatory mechanisms of the ECS in the substantia nigra (SN) of PD rats following STN-DBS.A research paper by scientists at Peking University Third Hospital presented a study on the regulatory mechanisms of the ECS in the substantia nigra (SN) of PD rats following STN-DBS.

An innovative strategy to produce bibenzyls from the deoxygenative homocoupling of benzyl alcohols under thea hydrogen atmosphere was developed using iron carbide catalysts. A variety of benzyl alcohols could be efficiently converted into the corresponding bibenzyls over the optimized Ir_0.1/Fe⁰@Fe₅C₂ catalyst, and a three-component coupling reaction mode was also discovered when alkenes were introduced. Based on control experiments and spectroscopy studies, a reaction mechanism involving C-O bond activation over iron carbide and the formation of benzyl radical species was proposed.