A new perspective article in Engineering explores the application of AI in process manufacturing. It examines how AI can be combined with process systems engineering tools, reviews current applications, and outlines challenges and opportunities, offering insights for a more efficient and sustainable manufacturing future.

A research paper by scientists at Shandong University presented a novel coordinated motion distribution and tracking algorithm for quadruped manipulators.

A study published in Engineering offers a practical risk-aware optimal dispatch strategy for resource aggregators. It aims to tackle the uncertainty of renewable energy and make use of building energy flexibility. The strategy combines probabilistic renewable energy prediction and a bi-level building flexibility engagement scheme, bringing economic and environmental benefits as shown by case studies.

A study in Engineering has developed a tin-modified Ce–Nb mixed-oxide catalyst. This catalyst shows enhanced performance in selective catalytic reduction of NO_x with NH₃, a key process for diesel vehicle emission control. It offers improved activity and hydrothermal stability, providing a potential solution for reducing nitrogen oxide emissions.

A major global study has found that pentoxifylline does not improve survival in patients with severe alcohol-associated hepatitis (sAH) complicated by acute kidney injury (AKI). Researchers analyzed 525 patients from 20 centers across eight countries and found no significant benefit in short- or long-term mortality outcomes with pentoxifylline use. The study underscores the limitations of this anti-inflammatory drug in the management of this critically ill population and highlights the urgent need for novel therapeutic strategies. Key predictors of mortality included age, Model for End-Stage Liver Disease (MELD) score, and need for renal replacement therapy, not pentoxifylline administration.

A research paper by scientists at Kyushu University presented a novel needle-free reagent injection method that improves the depth of reagent injection by reflecting shock waves through microbubble dynamics.

Medulloblastoma is the most common malignant pediatric brain tumor with a high risk of metastasis and poor survival outcomes. To delineate the metastatic microenvironment, researchers in China have developed an explainable machine learning model that identifies key immune cells and cytokine markers linked to tumor dissemination and prognosis. Their model offers a transparent, data-driven approach that could help clinicians better assess risk and personalize treatment for children with this life-threatening disease.

A team of researchers from West China Hospital of Sichuan University has uncovered a critical epigenetic mechanism that drives the development of osteoarthritis (OA), a debilitating joint disease affecting millions worldwide. Published in SCIENCE CHINA Life Sciences, their study reveals how articular cartilage, due to its shared developmental origin with growth plate cartilage, inherits epigenetic features that make it prone to degeneration. The findings also point to a promising new treatment strategy targeting a key epigenetic enzyme.