Millions suffer from xerostomia, or dry mouth—a painful condition often caused by cancer treatments or autoimmune disease.

The mechanisms underlying embryo implantation failure following in vitro fertilization (IVF), as well as low birth weight and offspring long-term health issues, have long been important unresolved questions. Now, writing in the journal Science Bulletin, a team of researchers from Tongji University, revealing that precisely regulating Wnt signaling during the peri-implantation period can enhances embryo implantation and improves post-implantation intrauterine development and postnatal phenotypes of IVF embryos. The findings provide a vital therapeutic target for enhancing IVF success rates, optimizing pregnancy outcomes, and addressing population growth challenges in clinical settings.

A research team sheds light on the intricate regulatory mechanisms governing anthocyanin biosynthesis in horticultural plants, offering insights that could enhance plant traits and agricultural productivity.

Discontinuous Deformation Analysis (DDA), a powerful tool for simulating the mechanical behavior of rock masses and discontinuous systems, has seen remarkable progress in recent 40 years. This article reviews DDA's evolution and explores how its integration with artificial intelligence (AI) could enhance simulation accuracy and computational efficiency.

On May 20, the 12th session of the “CACA Frontline Broadcast” academic conference, organized by the Chinese Anti-Cancer Association (CACA), concluded successfully in a hybrid format. During the conference, Professor He Jianxing and Professor Liang Wenhua's team from the First Affiliated Hospital of Guangzhou Medical University shared their research findings recently published in the Journal of the American Medical Association (JAMA), titled “Non–Risk-Based Lung Cancer Screening With Low-Dose Computed Tomography.” Professor He provided an in-depth overview of the study's background, rationale, and strategic considerations.

A peptide bridge is designed to construct a fusion enzyme with electrostatic cofactor channeling, reducing NADPH input by two orders of magnitude or decreasing reaction time threefold with the same cofactor input.

Newly sequenced ancient genomes from Yunnan, China, have shed new light on human prehistory in East Asia. In a study published in Science, a research team led by Prof. FU Qiaomei at the Institute of Vertebrate Paleontology and Paleoanthropology of the Chinese Academy of Sciences analyzed data from 127 ancient humans, dating from 7,100 to 1,400 years ago. The results show that this region is pivotal to understanding the origin of both Tibetan and Austroasiatic (i.e., ethnic groups with a shared language group in South and Southeast Asia) population groups.

Current commercial UV-emitting materials rely heavily on non-sustainable resources such as rare metals, heavy metals, and petroleum-based chemicals. Recently, carbon dots have been synthesized from a renewable feedstock—green tea extract. These carbon dots exhibit UV emission in water. Interestingly, in poorer solvents, their emission blue-shifts and becomes nearly five times more efficient due to aggregation-induced emission behavior.

Inspired by the suckerfishes-shark motion behavior, they designed and prepared a kind of NIR light-propelled micro@nanomotor with weak acid-triggered release of H₂O₂-driven nanomotor. By the coordinated bond interaction, a large amount of Janus Au-Pt nanomotors with hydrogen peroxide (H₂O₂)-driven capacity, analogous to suckerfishes, were attached onto immovable yolk-shell structured polydopamine-mesoporous silica (PDA-MS) micromotor as the host to create two-stage PDA-MS@Au-Pt micro@nanomotor. PDA-MS@Au-Pt micro@nanomotor moved directionally by self-thermophoresis under the propulsion of NIR light with low power density. When the PDA-MS@Au-Pt entered into the weak acidic environment formed by a low concentration of H₂O₂, most small Au-Pt nanomotors were detached from the surface of PDA-MS due to the weak acidic sensitivity of the coordinated bond, and then performed self-diffusiophoresis in the environment containing a low concentration of H₂O₂ as a chemical fuel.