Three years in, research shows regional, personal differences in use of 988 lifeline
Peer-Reviewed Publication
This month, we're turning our attention to National Suicide Prevention Awareness Month, an important time dedicated to raising awareness, breaking stigma, and exploring the science behind mental health and suicide prevention.
Updates every hour. Last Updated: 19-Sep-2025 02:11 ET (19-Sep-2025 06:11 GMT/UTC)
A groundbreaking new review comprehensively synthesizes the latest developments in next-generation chimeric antigen receptor T cell (CAR-T) therapies, highlighting key preclinical and clinical breakthroughs in the treatment of lymphoma. The article examines barriers to CAR-T efficacy and provides an in-depth analysis of innovative strategies, including multi-specific CAR, T cells redirected for universal cytokine-mediated killing (TRUCKs), switch receptor CAR, safety switch/suicide system, and in vivo CAR-T cells. With a special focus on the role of epigenetics and metabolism in CAR-T cell exhaustion, the review offers valuable insights and future directions for advancing CAR-T immunotherapy.
New research found that youth who become increasingly addicted to social media, mobile phones or video games are at greater risk of suicidal thoughts, suicide attempts and emotional or behavioral issues. The study, published June 18 in JAMA, was led by researchers at Weill Cornell Medicine, Columbia University and University of California, Berkeley.
Suicide is the third leading cause of death among young adults. But for those with intellectual and developmental disabilities (IDD), the crisis is even worse. A study highlights a critical yet overlooked public health crisis: the rising risk of suicide among young adults with IDD. Despite common misconceptions, individuals with IDD face heightened vulnerability due to social isolation, trauma, limited support, and systemic gaps in mental health care. The need for tailored prevention strategies is urgent to address this growing need.