3-Oct-2025
Construction and application of a halogen-bonded organic framework based on N⋯Cl+⋯N bond
Chinese Chemical SocietyPeer-Reviewed Publication
Prof. Shigui Chen's team at the Institute of Advanced Studies at Wuhan University recently achieved, through a step-by-step construction strategy, the stabilization of the [N⋯Cl⋯N]⁺ halogen bond at the framework level, thus breaking through the bottleneck of the inability of chlorine (I) halogen bonds to form bonds under conventional conditions and successfully constructed a class of stable chlorine (I) bridged two-dimensional halogen bond organic frameworks (XOF(Cl)-TPy-BF₄/OTf). This framework not only has excellent crystallinity, chemical stability and thermal stability, but also provides an ideal platform for subsequent functionalization (such as the introduction of catalytic sites). As a cationic framework, XOF(Cl) is anion-exchanged with PdCl₄²⁻ and then reduced to generate stable Pd(0) clusters within the framework. The Pd(0) cluster-loaded XOF(Cl)-TPy-Pd0 exhibits excellent catalytic performance in various palladium-catalyzed coupling reactions (such as Suzuki, Heck, and Sonogashira couplings), achieving high yields even under mild conditions. In the synthesis of industrial biphenyl liquid crystal molecules, no palladium residue was detected in XOF(Cl)-TPy-Pd0. In addition, the catalyst can be efficiently recovered by simple filtration and can be recycled many times, showing excellent practicality. These results were published as an open access article in CCS Chemistry, the flagship journal of the Chinese Chemical Society.
- Journal
- CCS Chemistry