Dear Experts and Colleagues,

    We are pleased to invite you to present and participate in our first annual Experimental Therapeutics at Ruijin meeting, to be held on June 1st to 4th,  2026, at Ruijin Hospital, Shanghai Jiao Tong University School of Medicine. Annual meeting will bring together leading investigators to share experiences in translating scientific discoveries into clinical success. We hope the event will provide every participant—faculty, students, and guests alike—with valuable insights and a stimulating exchange of ideas. The organizers are:

    H. Michael Shepard, PhD – Experimental Therapeutics Group, Ruijin Hospital, Shanghai

    Baiyong Shen, MD – Professor and Chief Physician, Ruijin Hospital, Shanghai

    Mone Zaidi, PhD – Icahn School of Medicine at Mount Sinai, New York

    We anticipate a high level of interest in this topic and will provide ample opportunity for meaningful interaction and discussion among participants. Some presentations will highlight programs with regulatory approval, while most will focus on those with preclinical or early clinical proof of concept.

    We sincerely hope you can join us for this exciting event in Shanghai.

    Time: June 1st to 4th, 2026

    Location: 1F Lecture Hall, Building 35, Translational Medicine Building, No. 197 Ruijin 2nd Road, Ruijin Hospital, Shanghai, China

    Contact: ying.zhang@jueqianmed.com

Artificial Intelligence + Education: Theory and Practice in Application Development is a work in the field of AI applications in education that combines cutting-edge theory with practical value for frontline educational practice.

Optical skyrmions hold promise for robust information carriers, yet existing technologies are limited to narrow-band generation. Scientists in China and Singapore invented an on-chip platform using ferroelectric spherulites. This device breaks the bandwidth limit by generating stable skyrmions across the entire visible spectrum. The technique paves the way for high-capacity optical communications and topological quantum light sources.

A widely used method for measuring how well streams absorb excess nutrients has a hidden flaw: it systematically overestimates uptake length under high-nutrient conditions. Researchers at Duke Kunshan University have derived a corrected zero-order analytical approach that better captures stream nutrient processing when nutrients are abundant, improving the accuracy of tools used to assess river health and guide restoration decisions.

This study highlights a practical formulation strategy to enhance the skin penetration of 10-hydroxy-2-decenoic acid (10H2DA), a key bioactive compound in royal jelly. By incorporating anionic cross-linked polymers, the authors achieved more than a tenfold increase in 10H2DA permeation compared with royal jelly extract alone. The study further confirmed epidermal penetration using DESI imaging mass spectrometry and demonstrated that higher skin hydration strongly promotes 10H2DA delivery. These findings emphasize that both formulation design and skin condition are critical for improving the dermal delivery of low-molecular-weight amphiphilic compounds.

Despite extensive development of flexible pressure sensors, it is still difficult for them to simultaneously achieve high precision and a large response to subtle pressures. To address these challenges, this work demonstrates a flexible pressure sensing platform that features the reduced graphene oxide aerogel sandwiched between a polydimethylsiloxane encapsulation layer and a thin polyimide film with interdigital electrodes. The resulting pressure sensor exhibits a high sensitivity of 698.96 kPa⁻¹ and a low limit of detection (~ 1 Pa), and outstanding stability over 20,000 loading/unloading cycles. Besides monitoring various physiological signals and human motions, the flexible pressure sensors can be configured into an array layout as a smart artificial electronic skin to recognize the spatial pressure distribution. The flexible pressure sensor can also be integrated with signal processing and wireless communication modules as a teleoperation system for gesture recognition, force feedback control, and kitchen food recognition, highlighting future potential toward smart robotics and human–machine interfaces.